Abstract
Objective: To investigate whether the protection observed for some micronutrients, such as beta-carotene, in several observational studies may simply reflect vegetable and fruit intake. Design: A case-control study conducted in Italy. Subjects: The subjects were 1225 colon cancer patients, 728 rectal cancer patients and 4154 hospital controls. Results: For the 16 micronutrients considered, the more closely a micronutrient was correlated with total vegetable and fruit intake, the more it appeared protective against colorectal cancer. Conclusion: When studying the effect of a nutrient on disease risk in an observational setting, its relation to other nutrients and foods must be taken into account.
| Original language | English |
|---|---|
| Pages (from-to) | 166-170 |
| Number of pages | 5 |
| Journal | European Journal of Clinical Nutrition |
| Volume | 56 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2002 |
Keywords
- Cancer
- Case-control studies
- Diet
- Micronutrients
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Food Science
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Negri, E., La Vecchia, C., & Franceschi, S. (2002). Relations between vegetable, fruit and micronutrient intake. Implications for odds ratios in a case-control study. European Journal of Clinical Nutrition, 56(2), 166-170. https://doi.org/10.1038/sj/ejcn/1601