TY - JOUR
T1 - Relations between vegetable, fruit and micronutrient intake. Implications for odds ratios in a case-control study
AU - Negri, E.
AU - La Vecchia, C.
AU - Franceschi, S.
PY - 2002
Y1 - 2002
N2 - Objective: To investigate whether the protection observed for some micronutrients, such as beta-carotene, in several observational studies may simply reflect vegetable and fruit intake. Design: A case-control study conducted in Italy. Subjects: The subjects were 1225 colon cancer patients, 728 rectal cancer patients and 4154 hospital controls. Results: For the 16 micronutrients considered, the more closely a micronutrient was correlated with total vegetable and fruit intake, the more it appeared protective against colorectal cancer. Conclusion: When studying the effect of a nutrient on disease risk in an observational setting, its relation to other nutrients and foods must be taken into account.
AB - Objective: To investigate whether the protection observed for some micronutrients, such as beta-carotene, in several observational studies may simply reflect vegetable and fruit intake. Design: A case-control study conducted in Italy. Subjects: The subjects were 1225 colon cancer patients, 728 rectal cancer patients and 4154 hospital controls. Results: For the 16 micronutrients considered, the more closely a micronutrient was correlated with total vegetable and fruit intake, the more it appeared protective against colorectal cancer. Conclusion: When studying the effect of a nutrient on disease risk in an observational setting, its relation to other nutrients and foods must be taken into account.
KW - Cancer
KW - Case-control studies
KW - Diet
KW - Micronutrients
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U2 - 10.1038/sj/ejcn/1601
DO - 10.1038/sj/ejcn/1601
M3 - Article
C2 - 11857050
VL - 56
SP - 166
EP - 170
JO - European Journal of Clinical Nutrition
JF - European Journal of Clinical Nutrition
SN - 0954-3007
IS - 2
ER -