Abstract
Objective: To investigate whether the protection observed for some micronutrients, such as beta-carotene, in several observational studies may simply reflect vegetable and fruit intake. Design: A case-control study conducted in Italy. Subjects: The subjects were 1225 colon cancer patients, 728 rectal cancer patients and 4154 hospital controls. Results: For the 16 micronutrients considered, the more closely a micronutrient was correlated with total vegetable and fruit intake, the more it appeared protective against colorectal cancer. Conclusion: When studying the effect of a nutrient on disease risk in an observational setting, its relation to other nutrients and foods must be taken into account.
| Original language | English |
|---|---|
| Pages (from-to) | 166-170 |
| Number of pages | 5 |
| Journal | European Journal of Clinical Nutrition |
| Volume | 56 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2002 |
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Keywords
- Cancer
- Case-control studies
- Diet
- Micronutrients
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Food Science
Cite this
Relations between vegetable, fruit and micronutrient intake. Implications for odds ratios in a case-control study. / Negri, E.; La Vecchia, C.; Franceschi, S.
In: European Journal of Clinical Nutrition, Vol. 56, No. 2, 2002, p. 166-170.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Relations between vegetable, fruit and micronutrient intake. Implications for odds ratios in a case-control study
AU - Negri, E.
AU - La Vecchia, C.
AU - Franceschi, S.
PY - 2002
Y1 - 2002
N2 - Objective: To investigate whether the protection observed for some micronutrients, such as beta-carotene, in several observational studies may simply reflect vegetable and fruit intake. Design: A case-control study conducted in Italy. Subjects: The subjects were 1225 colon cancer patients, 728 rectal cancer patients and 4154 hospital controls. Results: For the 16 micronutrients considered, the more closely a micronutrient was correlated with total vegetable and fruit intake, the more it appeared protective against colorectal cancer. Conclusion: When studying the effect of a nutrient on disease risk in an observational setting, its relation to other nutrients and foods must be taken into account.
AB - Objective: To investigate whether the protection observed for some micronutrients, such as beta-carotene, in several observational studies may simply reflect vegetable and fruit intake. Design: A case-control study conducted in Italy. Subjects: The subjects were 1225 colon cancer patients, 728 rectal cancer patients and 4154 hospital controls. Results: For the 16 micronutrients considered, the more closely a micronutrient was correlated with total vegetable and fruit intake, the more it appeared protective against colorectal cancer. Conclusion: When studying the effect of a nutrient on disease risk in an observational setting, its relation to other nutrients and foods must be taken into account.
KW - Cancer
KW - Case-control studies
KW - Diet
KW - Micronutrients
UR - http://www.scopus.com/inward/record.url?scp=0036172659&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036172659&partnerID=8YFLogxK
U2 - 10.1038/sj/ejcn/1601
DO - 10.1038/sj/ejcn/1601
M3 - Article
C2 - 11857050
VL - 56
SP - 166
EP - 170
JO - European Journal of Clinical Nutrition
JF - European Journal of Clinical Nutrition
SN - 0954-3007
IS - 2
ER -