Relationship between apathy and cognitive dysfunctions in de novo untreated Parkinson's disease: A prospective longitudinal study

G. Santangelo, C. Vitale, L. Trojano, M. Picillo, M. Moccia, G. Pisano, D. Pezzella, S. Cuoco, R. Erro, K. Longo, M. T. Pellecchia, M. Amboni, A. De Rosa, G. De Michele, P. Barone

Research output: Contribution to journalArticlepeer-review

Abstract

Background and purpose: Apathy may be either a symptom of major depression or a behavioral disturbance occurring in concomitance with depression or alone in Parkinson's disease (PD). The aim of the present study was to determine the progression of cognitive impairment in drug-naïve untreated PD patients with or without clinically significant apathy. Methods: Sixty-two PD patients with a disease duration

Original languageEnglish
Pages (from-to)253-260
Number of pages8
JournalEuropean Journal of Neurology
Volume22
Issue number2
DOIs
Publication statusPublished - Feb 1 2015

Keywords

  • Apathy
  • Behavioral disorders
  • Cognitive dysfunctions
  • Frontal dysfunctions
  • Parkinson's disease

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

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