Relationship between arterial potassium and ventilation during exercise in patients with chronic heart failure

Andrew L. Clark; Maurizio Volterrani; Elena Cerquetani; Peter Ludman; Jonathan W. Swan; Philip A. Poole-Wilson; Andrew J S Coats

doi:10.1016/1071-9164(95)90015-2

Relationship between arterial potassium and ventilation during exercise in patients with chronic heart failure

Andrew L. Clark, Maurizio Volterrani, Elena Cerquetani, Peter Ludman, Jonathan W. Swan, Philip A. Poole-Wilson, Andrew J S Coats

Istituto San Raffaele Pisana

Research output: Contribution to journal › Article › peer-review

Abstract

The mechanisms underlying the increased ventilatory response to exercise seen in patients with chronic heart failure are not clearly understood. Arterial potassium has been suggested as an important ventilatory stimulant. The authors have investigated the arterial potassium response in patients with heart failure. Although arterial potassium rises during exercise, no evidence was found to suggest a greater potassium response in patients with heart failure compared to normal subjects. There was no direct correlation between the rise in ventilation and the rise in arterial potassium. It remains possible that there is an increased sensitivity to arterial potassium in patients with heart failure, but it would need to be three times greater than in normal subjects.

Original language	English
Pages (from-to)	133-141
Number of pages	9
Journal	Journal of Cardiac Failure
Volume	1
Issue number	2
DOIs	https://doi.org/10.1016/1071-9164(95)90015-2
Publication status	Published - 1995

Keywords

heart failure
metabolic gas exchange
ventilation

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/1071-9164(95)90015-2

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title = "Relationship between arterial potassium and ventilation during exercise in patients with chronic heart failure",

abstract = "The mechanisms underlying the increased ventilatory response to exercise seen in patients with chronic heart failure are not clearly understood. Arterial potassium has been suggested as an important ventilatory stimulant. The authors have investigated the arterial potassium response in patients with heart failure. Although arterial potassium rises during exercise, no evidence was found to suggest a greater potassium response in patients with heart failure compared to normal subjects. There was no direct correlation between the rise in ventilation and the rise in arterial potassium. It remains possible that there is an increased sensitivity to arterial potassium in patients with heart failure, but it would need to be three times greater than in normal subjects.",

keywords = "heart failure, metabolic gas exchange, ventilation",

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T1 - Relationship between arterial potassium and ventilation during exercise in patients with chronic heart failure

AU - Clark, Andrew L.

AU - Volterrani, Maurizio

AU - Cerquetani, Elena

AU - Ludman, Peter

AU - Swan, Jonathan W.

AU - Poole-Wilson, Philip A.

AU - Coats, Andrew J S

PY - 1995

Y1 - 1995

N2 - The mechanisms underlying the increased ventilatory response to exercise seen in patients with chronic heart failure are not clearly understood. Arterial potassium has been suggested as an important ventilatory stimulant. The authors have investigated the arterial potassium response in patients with heart failure. Although arterial potassium rises during exercise, no evidence was found to suggest a greater potassium response in patients with heart failure compared to normal subjects. There was no direct correlation between the rise in ventilation and the rise in arterial potassium. It remains possible that there is an increased sensitivity to arterial potassium in patients with heart failure, but it would need to be three times greater than in normal subjects.

AB - The mechanisms underlying the increased ventilatory response to exercise seen in patients with chronic heart failure are not clearly understood. Arterial potassium has been suggested as an important ventilatory stimulant. The authors have investigated the arterial potassium response in patients with heart failure. Although arterial potassium rises during exercise, no evidence was found to suggest a greater potassium response in patients with heart failure compared to normal subjects. There was no direct correlation between the rise in ventilation and the rise in arterial potassium. It remains possible that there is an increased sensitivity to arterial potassium in patients with heart failure, but it would need to be three times greater than in normal subjects.

KW - heart failure

KW - metabolic gas exchange

KW - ventilation

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Relationship between arterial potassium and ventilation during exercise in patients with chronic heart failure

Abstract

Keywords

ASJC Scopus subject areas

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