Relationship between arterial potassium and ventilation during exercise in patients with chronic heart failure

Andrew L. Clark, Maurizio Volterrani, Elena Cerquetani, Peter Ludman, Jonathan W. Swan, Philip A. Poole-Wilson, Andrew J S Coats

Research output: Contribution to journalArticlepeer-review

Abstract

The mechanisms underlying the increased ventilatory response to exercise seen in patients with chronic heart failure are not clearly understood. Arterial potassium has been suggested as an important ventilatory stimulant. The authors have investigated the arterial potassium response in patients with heart failure. Although arterial potassium rises during exercise, no evidence was found to suggest a greater potassium response in patients with heart failure compared to normal subjects. There was no direct correlation between the rise in ventilation and the rise in arterial potassium. It remains possible that there is an increased sensitivity to arterial potassium in patients with heart failure, but it would need to be three times greater than in normal subjects.

Original languageEnglish
Pages (from-to)133-141
Number of pages9
JournalJournal of Cardiac Failure
Volume1
Issue number2
DOIs
Publication statusPublished - 1995

Keywords

  • heart failure
  • metabolic gas exchange
  • ventilation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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