Relationship between biofilm formation, the enterococcal surface protein (Esp) and gelatinase in clinical isolates of Enterococcus faecalis and Enterococcus faecium

Roberta Di Rosa, Roberta Creti, Mario Venditti, Raffaele D'Amelio, Carlar Arciola, Lucio Montanaro, Lucilla Baldassarri

Research output: Contribution to journalArticle

Abstract

One-hundred and twenty-eight enterococcal isolates were examined for their ability to form biofilm in relation to the presence of the gene encoding the enterococcal surface protein (esp), production of gelatinase and to the source of isolation. Neither esp nor gelatinase seemed to be required for biofilm formation: both Enterococcus faecalis and Enterococcus faecium did not show a correlation between the presence of either esp or the production of gelatinase and biofilm formation. However, in E. faecium while esp was found in isolates from either source, the presence of both esp and biofilm together was only found in strains from clinical settings, suggesting that there exists a synergy between these factors which serves as an advantage for the process of infection.

Original languageEnglish
Pages (from-to)145-150
Number of pages6
JournalFEMS Microbiology Letters
Volume256
Issue number1
DOIs
Publication statusPublished - Mar 2006

Keywords

  • Biofilm
  • Enterococci
  • Esp
  • Gelatinase
  • Virulence

ASJC Scopus subject areas

  • Genetics
  • Molecular Biology
  • Applied Microbiology and Biotechnology
  • Microbiology

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