Relationship between diabetes and respiratory diseases-Clinical and therapeutic aspects

D Visca, P Pignatti, A Spanevello, E Lucini, E La Rocca

Research output: Contribution to journalReview article

Abstract

Diabetes is a common metabolic disorder affecting the entire body with high morbidity and mortality worldwide. The major complications related to diabetes are mostly due to the macrovascular and microvascular bed impairment due to metabolic, hemodynamic and inflammatory factors. However, studies over the past decades have added also the lung as a target organ in both type 1 and type 2 diabetes. Diabetes has always been addressed as a major comorbidity conditioning the disease behaviour and the natural history of several respiratory diseases. Increased interest has recently focused on the pathophysiology of the metabolic glycaemic disorder and the respiratory diseases suggesting a similar background shared by the two conditions. The true relationship between pulmonary diseases and diabetes mellitus has not been clarified, this review aims to summarize the link between diabetes and coexisting respiratory diseases such as asthma, chronic obstructive pulmonary disease, respiratory infections, cystic fibrosis, lung cancer and obstructive sleep apnea from a pathogenetic and therapeutic point of view.

Original languageEnglish
Pages (from-to)230-235
Number of pages6
JournalPharmacological Research
Volume137
DOIs
Publication statusPublished - Nov 2018

Fingerprint

Obstructive Sleep Apnea
Diabetes Complications
Therapeutics
Type 1 Diabetes Mellitus
Cystic Fibrosis
Respiratory Tract Infections
Chronic Obstructive Pulmonary Disease
Type 2 Diabetes Mellitus
Lung Diseases
Comorbidity
Lung Neoplasms
Diabetes Mellitus
Asthma
Hemodynamics
Morbidity
Lung
Mortality

Cite this

Relationship between diabetes and respiratory diseases-Clinical and therapeutic aspects. / Visca, D; Pignatti, P; Spanevello, A; Lucini, E; La Rocca, E.

In: Pharmacological Research, Vol. 137, 11.2018, p. 230-235.

Research output: Contribution to journalReview article

@article{c7ae2569c1994581862d00cabffbc76b,
title = "Relationship between diabetes and respiratory diseases-Clinical and therapeutic aspects",
abstract = "Diabetes is a common metabolic disorder affecting the entire body with high morbidity and mortality worldwide. The major complications related to diabetes are mostly due to the macrovascular and microvascular bed impairment due to metabolic, hemodynamic and inflammatory factors. However, studies over the past decades have added also the lung as a target organ in both type 1 and type 2 diabetes. Diabetes has always been addressed as a major comorbidity conditioning the disease behaviour and the natural history of several respiratory diseases. Increased interest has recently focused on the pathophysiology of the metabolic glycaemic disorder and the respiratory diseases suggesting a similar background shared by the two conditions. The true relationship between pulmonary diseases and diabetes mellitus has not been clarified, this review aims to summarize the link between diabetes and coexisting respiratory diseases such as asthma, chronic obstructive pulmonary disease, respiratory infections, cystic fibrosis, lung cancer and obstructive sleep apnea from a pathogenetic and therapeutic point of view.",
author = "D Visca and P Pignatti and A Spanevello and E Lucini and {La Rocca}, E",
note = "Copyright {\circledC} 2018. Published by Elsevier Ltd.",
year = "2018",
month = "11",
doi = "10.1016/j.phrs.2018.10.008",
language = "English",
volume = "137",
pages = "230--235",
journal = "Pharmacological Research",
issn = "1043-6618",
publisher = "Academic Press",

}

TY - JOUR

T1 - Relationship between diabetes and respiratory diseases-Clinical and therapeutic aspects

AU - Visca, D

AU - Pignatti, P

AU - Spanevello, A

AU - Lucini, E

AU - La Rocca, E

N1 - Copyright © 2018. Published by Elsevier Ltd.

PY - 2018/11

Y1 - 2018/11

N2 - Diabetes is a common metabolic disorder affecting the entire body with high morbidity and mortality worldwide. The major complications related to diabetes are mostly due to the macrovascular and microvascular bed impairment due to metabolic, hemodynamic and inflammatory factors. However, studies over the past decades have added also the lung as a target organ in both type 1 and type 2 diabetes. Diabetes has always been addressed as a major comorbidity conditioning the disease behaviour and the natural history of several respiratory diseases. Increased interest has recently focused on the pathophysiology of the metabolic glycaemic disorder and the respiratory diseases suggesting a similar background shared by the two conditions. The true relationship between pulmonary diseases and diabetes mellitus has not been clarified, this review aims to summarize the link between diabetes and coexisting respiratory diseases such as asthma, chronic obstructive pulmonary disease, respiratory infections, cystic fibrosis, lung cancer and obstructive sleep apnea from a pathogenetic and therapeutic point of view.

AB - Diabetes is a common metabolic disorder affecting the entire body with high morbidity and mortality worldwide. The major complications related to diabetes are mostly due to the macrovascular and microvascular bed impairment due to metabolic, hemodynamic and inflammatory factors. However, studies over the past decades have added also the lung as a target organ in both type 1 and type 2 diabetes. Diabetes has always been addressed as a major comorbidity conditioning the disease behaviour and the natural history of several respiratory diseases. Increased interest has recently focused on the pathophysiology of the metabolic glycaemic disorder and the respiratory diseases suggesting a similar background shared by the two conditions. The true relationship between pulmonary diseases and diabetes mellitus has not been clarified, this review aims to summarize the link between diabetes and coexisting respiratory diseases such as asthma, chronic obstructive pulmonary disease, respiratory infections, cystic fibrosis, lung cancer and obstructive sleep apnea from a pathogenetic and therapeutic point of view.

U2 - 10.1016/j.phrs.2018.10.008

DO - 10.1016/j.phrs.2018.10.008

M3 - Review article

C2 - 30312663

VL - 137

SP - 230

EP - 235

JO - Pharmacological Research

JF - Pharmacological Research

SN - 1043-6618

ER -