Relationship between exercise capacity, endothelial progenitor cells and cytochemokines in patients undergoing cardiac rehabilitation

Francesca Cesari, Francesco Sofi, Roberto Caporale, Andrea Capalbo, Rossella Marcucci, Claudio Macchi, Raffaele Molino Lova, Tommaso Cellai, Mauro Vannucci, Gian Franco Gensini, Rosanna Abbate, Anna Maria Gori

Research output: Contribution to journalArticlepeer-review

Abstract

No data are available about the possible role of endothelial progenitor cells (EPCs), cytochemokines and N-terminal pro-brain natriuretic peptide (NT-proBNP) in determining a different response to short period of cardiologic rehabilitation (CR), as measured by the improvement of exercise capacity. In a population of 86 cardiac surgery patients, we evaluated the numbers of EPCs, pro- and anti-inflammatory cytokines (IL-6,IL-8, IL-10, IL-Ira), hs-C-reactive protein (CRP), vascular endothelial growth factor (VEGF) and NT-proBNP before (Tl ),and after 15 days of CR (T2). EPCs were measured by flow cytometry, and the exercise capacity was measured at T1 andT2 by using the six-minute walk test (6MWT).At T2, a significant increase of 6MWT (p

Original languageEnglish
Pages (from-to)521-526
Number of pages6
JournalThrombosis and Haemostasis
Volume101
Issue number3
DOIs
Publication statusPublished - Mar 2009

Keywords

  • Cardiac rehabilitation
  • Cytochemokines
  • Endothelial progenitor cells
  • Exercise capacity

ASJC Scopus subject areas

  • Hematology

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