Abstract
Fibrin clot retraction (FCR) was studied in C3H/10T1/2 murine fibroblasts. These cells were able to induce FCR with high efficiency during resting phase as well as during active growth. C3H/10T1/2 cells which became tumorigenic after X-irradiation lacked FCR activity. Non-tumorigenic revertant clones regained the capacity to induce FCR, while revertants which progressively back-reverted to the neoplastic state showed intermediate FCR activity. These unstable revertants, when again fully tumorigenic, completely lost FCR activity.
| Original language | English |
|---|---|
| Pages (from-to) | 799-803 |
| Number of pages | 5 |
| Journal | International Journal of Cancer |
| Volume | 28 |
| Issue number | 6 |
| Publication status | Published - 1981 |
ASJC Scopus subject areas
- Cancer Research
- Oncology