Relationship between infarct size and severity measured by gated SPECT and long-term left ventricular remodelling after acute myocardial infarction

Valentina Berti; Roberto Sciagrà; Wanda Acampa; Francesca Ricci; Giampaolo Cerisano; Rosj Gallicchio; Carlo Vigorito; Alberto Pupi; Alberto Cuocolo

doi:10.1007/s00259-011-1739-7

Relationship between infarct size and severity measured by gated SPECT and long-term left ventricular remodelling after acute myocardial infarction

Valentina Berti, Roberto Sciagrà, Wanda Acampa, Francesca Ricci, Giampaolo Cerisano, Rosj Gallicchio, Carlo Vigorito, Alberto Pupi, Alberto Cuocolo

Research output: Contribution to journal › Article › peer-review

Abstract

Purpose: After acute myocardial infarction (AMI), left ventricular (LV) remodelling may occur despite successful reperfusion. This study aimed to investigate by gated single photon emission computed tomography (SPECT) the long-term evolution of myocardial perfusion and LV function after AMI and to identify the predictors of LV remodelling. Methods: Sixty-eight AMI patients successfully treated by primary percutaneous coronary intervention underwent ^99mTc-sestamibi gated SPECT at 1 month (baseline) and over 6-month follow-up after the acute event. LV remodelling was defined as 20% increase in LV end-diastolic volume at follow-up. Results: At baseline, patients with remodelling (n=14) showed larger (infarct size 29.3±7.8%) and more transmural (infarct severity 0.28±0.10) infarctions, and reduced LV ejection fraction (35.4±5.6%), but similar LV volume indexes, compared to patients without remodelling (n=54) (infarct size 20.8±14.4%, p

Original language	English
Pages (from-to)	1124-1131
Number of pages	8
Journal	European Journal of Nuclear Medicine and Molecular Imaging
Volume	38
Issue number	6
DOIs	https://doi.org/10.1007/s00259-011-1739-7
Publication status	Published - Jun 2011

Keywords

Acute myocardial infarction
Left ventricular function
Myocardial perfusion
Ventricular remodelling

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1007/s00259-011-1739-7

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Berti, V., Sciagrà, R., Acampa, W., Ricci, F., Cerisano, G., Gallicchio, R., Vigorito, C., Pupi, A., & Cuocolo, A. (2011). Relationship between infarct size and severity measured by gated SPECT and long-term left ventricular remodelling after acute myocardial infarction. European Journal of Nuclear Medicine and Molecular Imaging, 38(6), 1124-1131. https://doi.org/10.1007/s00259-011-1739-7

Relationship between infarct size and severity measured by gated SPECT and long-term left ventricular remodelling after acute myocardial infarction. / Berti, Valentina; Sciagrà, Roberto; Acampa, Wanda; Ricci, Francesca; Cerisano, Giampaolo; Gallicchio, Rosj; Vigorito, Carlo; Pupi, Alberto; Cuocolo, Alberto.

In: European Journal of Nuclear Medicine and Molecular Imaging, Vol. 38, No. 6, 06.2011, p. 1124-1131.

Research output: Contribution to journal › Article › peer-review

Berti, V, Sciagrà, R, Acampa, W, Ricci, F, Cerisano, G, Gallicchio, R, Vigorito, C, Pupi, A & Cuocolo, A 2011, 'Relationship between infarct size and severity measured by gated SPECT and long-term left ventricular remodelling after acute myocardial infarction', European Journal of Nuclear Medicine and Molecular Imaging, vol. 38, no. 6, pp. 1124-1131. https://doi.org/10.1007/s00259-011-1739-7

Berti, Valentina ; Sciagrà, Roberto ; Acampa, Wanda ; Ricci, Francesca ; Cerisano, Giampaolo ; Gallicchio, Rosj ; Vigorito, Carlo ; Pupi, Alberto ; Cuocolo, Alberto. / Relationship between infarct size and severity measured by gated SPECT and long-term left ventricular remodelling after acute myocardial infarction. In: European Journal of Nuclear Medicine and Molecular Imaging. 2011 ; Vol. 38, No. 6. pp. 1124-1131.

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