TY - JOUR
T1 - Relationship between infarct size and severity measured by gated SPECT and long-term left ventricular remodelling after acute myocardial infarction
AU - Berti, Valentina
AU - Sciagrà, Roberto
AU - Acampa, Wanda
AU - Ricci, Francesca
AU - Cerisano, Giampaolo
AU - Gallicchio, Rosj
AU - Vigorito, Carlo
AU - Pupi, Alberto
AU - Cuocolo, Alberto
PY - 2011/6
Y1 - 2011/6
N2 - Purpose: After acute myocardial infarction (AMI), left ventricular (LV) remodelling may occur despite successful reperfusion. This study aimed to investigate by gated single photon emission computed tomography (SPECT) the long-term evolution of myocardial perfusion and LV function after AMI and to identify the predictors of LV remodelling. Methods: Sixty-eight AMI patients successfully treated by primary percutaneous coronary intervention underwent 99mTc-sestamibi gated SPECT at 1 month (baseline) and over 6-month follow-up after the acute event. LV remodelling was defined as 20% increase in LV end-diastolic volume at follow-up. Results: At baseline, patients with remodelling (n=14) showed larger (infarct size 29.3±7.8%) and more transmural (infarct severity 0.28±0.10) infarctions, and reduced LV ejection fraction (35.4±5.6%), but similar LV volume indexes, compared to patients without remodelling (n=54) (infarct size 20.8±14.4%, p
AB - Purpose: After acute myocardial infarction (AMI), left ventricular (LV) remodelling may occur despite successful reperfusion. This study aimed to investigate by gated single photon emission computed tomography (SPECT) the long-term evolution of myocardial perfusion and LV function after AMI and to identify the predictors of LV remodelling. Methods: Sixty-eight AMI patients successfully treated by primary percutaneous coronary intervention underwent 99mTc-sestamibi gated SPECT at 1 month (baseline) and over 6-month follow-up after the acute event. LV remodelling was defined as 20% increase in LV end-diastolic volume at follow-up. Results: At baseline, patients with remodelling (n=14) showed larger (infarct size 29.3±7.8%) and more transmural (infarct severity 0.28±0.10) infarctions, and reduced LV ejection fraction (35.4±5.6%), but similar LV volume indexes, compared to patients without remodelling (n=54) (infarct size 20.8±14.4%, p
KW - Acute myocardial infarction
KW - Left ventricular function
KW - Myocardial perfusion
KW - Ventricular remodelling
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U2 - 10.1007/s00259-011-1739-7
DO - 10.1007/s00259-011-1739-7
M3 - Article
C2 - 21327635
AN - SCOPUS:79958048849
VL - 38
SP - 1124
EP - 1131
JO - European Journal of Pediatrics
JF - European Journal of Pediatrics
SN - 0340-6199
IS - 6
ER -