Relationship between inflammatory food consumption and age-related hearing loss in a prospective observational cohort: Results from the salus in Apulia study

Rodolfo Sardone, Luisa Lampignano, Vito Guerra, Roberta Zupo, Rossella Donghia, Fabio Castellana, Petronilla Battista, Ilaria Bortone, Filippo Procino, Marco Castellana, Andrea Passantino, Roberta Rucco, Madia Lozupone, Davide Seripa, Francesco Panza, Giovanni De Pergola, Gianluigi Giannelli, Giancarlo Logroscino, Heiner Boeing, Nicola Quaranta

Research output: Contribution to journalArticle

Abstract

Age related hearing loss (ARHL) affects about one third of the elderly population. It is suggested that the senescence of the hair cells could be modulated by inflammation. Thus, intake of anti-and pro-inflammatory foods is of high interest. Methods: From the MICOL study population, 734 participants were selected that participated in the 2013 to 2018 examination including hearing ability and from which past data collected in 2005/2008 was available. ARHL status was determined and compared cross-sectionally and retrospectively according to clinical and lifestyle data including food and micronutrient intake. Results: ARHL status was associated with higher age but not with education, smoking, relative weight (BMI), and clinical-chemical blood markers in the crossectional and retrospective analyses. Higher intake of fruit juices among ARHL-participants was seen cross-sectionally, and of sugary foods, high-caloric drinks, beer, and spirits retrospectively. No difference was found for the other 26 food groups and for dietary micronutrients with the exception of past vitamin A, which was higher among normal hearing subjects. Conclusions: Pro-inflammatory foods with a high-sugar content and also beer and spirits were found to be assocated with positive ARHL-status, but not anti-inflammatory foods. Diet could be a candidate for lifestyle advice for the prevention of ARHL.

Original languageEnglish
Article number426
JournalNutrients
Volume12
Issue number2
DOIs
Publication statusPublished - Feb 2020

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Keywords

  • Age-related hearing loss
  • Alcohol
  • Diet
  • Food
  • Inflammation
  • Population studies
  • Presbycusis
  • Sugar

ASJC Scopus subject areas

  • Food Science
  • Nutrition and Dietetics

Cite this

Sardone, R., Lampignano, L., Guerra, V., Zupo, R., Donghia, R., Castellana, F., Battista, P., Bortone, I., Procino, F., Castellana, M., Passantino, A., Rucco, R., Lozupone, M., Seripa, D., Panza, F., De Pergola, G., Giannelli, G., Logroscino, G., Boeing, H., & Quaranta, N. (2020). Relationship between inflammatory food consumption and age-related hearing loss in a prospective observational cohort: Results from the salus in Apulia study. Nutrients, 12(2), [426]. https://doi.org/10.3390/nu12020426