TY - JOUR
T1 - Relationship between inflammatory food consumption and age-related hearing loss in a prospective observational cohort
T2 - Results from the salus in Apulia study
AU - Sardone, Rodolfo
AU - Lampignano, Luisa
AU - Guerra, Vito
AU - Zupo, Roberta
AU - Donghia, Rossella
AU - Castellana, Fabio
AU - Battista, Petronilla
AU - Bortone, Ilaria
AU - Procino, Filippo
AU - Castellana, Marco
AU - Passantino, Andrea
AU - Rucco, Roberta
AU - Lozupone, Madia
AU - Seripa, Davide
AU - Panza, Francesco
AU - De Pergola, Giovanni
AU - Giannelli, Gianluigi
AU - Logroscino, Giancarlo
AU - Boeing, Heiner
AU - Quaranta, Nicola
N1 - Funding Information:
Funding: This study was funded by the Italian Ministry of Health with “Ricerca Corrente 2019 Grant”.
Publisher Copyright:
© 2020 by the authors. Licensee MDPI, Basel, Switzerland.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/2
Y1 - 2020/2
N2 - Age related hearing loss (ARHL) affects about one third of the elderly population. It is suggested that the senescence of the hair cells could be modulated by inflammation. Thus, intake of anti-and pro-inflammatory foods is of high interest. Methods: From the MICOL study population, 734 participants were selected that participated in the 2013 to 2018 examination including hearing ability and from which past data collected in 2005/2008 was available. ARHL status was determined and compared cross-sectionally and retrospectively according to clinical and lifestyle data including food and micronutrient intake. Results: ARHL status was associated with higher age but not with education, smoking, relative weight (BMI), and clinical-chemical blood markers in the crossectional and retrospective analyses. Higher intake of fruit juices among ARHL-participants was seen cross-sectionally, and of sugary foods, high-caloric drinks, beer, and spirits retrospectively. No difference was found for the other 26 food groups and for dietary micronutrients with the exception of past vitamin A, which was higher among normal hearing subjects. Conclusions: Pro-inflammatory foods with a high-sugar content and also beer and spirits were found to be assocated with positive ARHL-status, but not anti-inflammatory foods. Diet could be a candidate for lifestyle advice for the prevention of ARHL.
AB - Age related hearing loss (ARHL) affects about one third of the elderly population. It is suggested that the senescence of the hair cells could be modulated by inflammation. Thus, intake of anti-and pro-inflammatory foods is of high interest. Methods: From the MICOL study population, 734 participants were selected that participated in the 2013 to 2018 examination including hearing ability and from which past data collected in 2005/2008 was available. ARHL status was determined and compared cross-sectionally and retrospectively according to clinical and lifestyle data including food and micronutrient intake. Results: ARHL status was associated with higher age but not with education, smoking, relative weight (BMI), and clinical-chemical blood markers in the crossectional and retrospective analyses. Higher intake of fruit juices among ARHL-participants was seen cross-sectionally, and of sugary foods, high-caloric drinks, beer, and spirits retrospectively. No difference was found for the other 26 food groups and for dietary micronutrients with the exception of past vitamin A, which was higher among normal hearing subjects. Conclusions: Pro-inflammatory foods with a high-sugar content and also beer and spirits were found to be assocated with positive ARHL-status, but not anti-inflammatory foods. Diet could be a candidate for lifestyle advice for the prevention of ARHL.
KW - Age-related hearing loss
KW - Alcohol
KW - Diet
KW - Food
KW - Inflammation
KW - Population studies
KW - Presbycusis
KW - Sugar
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U2 - 10.3390/nu12020426
DO - 10.3390/nu12020426
M3 - Article
C2 - 32046004
AN - SCOPUS:85079307318
VL - 12
JO - Nutrients
JF - Nutrients
SN - 2072-6643
IS - 2
M1 - 426
ER -