Relationship between rhinitis duration and worsening of nasal function

Giorgio Ciprandi, Ignazio Cirillo, Angela Pistorio, Stefania La Grutta

Research output: Contribution to journalArticlepeer-review


Background: While it is well known that asthma is characterized by airway remodeling, few studies instead have investigated this issue in patients with allergic rhinitis (AR). Objective: The aim of the study was to evaluate nasal function, ie, nasal airflow, in a cohort of patients with persistent AR (PER). Methods: One hundred patients, 50 with short-term and 50 with long-term PER, were prospectively and consecutively evaluated, clinically evaluated by visit, skin prick test, and rhinomanometry. Results: Nasal airflow values were significantly lower (median flow: 348 mL/sec) in patients with long-term rhinitis (median duration nine years) as compared to patients with short-term (median duration one year) rhinitis (median flow: 466 mL/sec) (P <0.0001). Conclusion: This study provides the first evidence that patients with PER may show a progressive worsening of nasal airflow depending on the duration of the disorder.

Original languageEnglish
Pages (from-to)725-729
Number of pages5
JournalOtolaryngology - Head and Neck Surgery
Issue number6
Publication statusPublished - Jun 2008

ASJC Scopus subject areas

  • Otorhinolaryngology


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