Relationship between ventilatory oscillations and fractal dimension of the EEG during daytime periodic breathing in heart failure patients

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this study we investigated the existence and the nature of rhythmic changes in EEG associated with ventilatory oscillations in heart failure (HF) patients with periodic breathing (PB). Since nonlinear mechanisms are thought to be involved in the generation of EEG, we hypothesized that a mathematical approach based on nonlinear methods would provide relevant information on the association between EEG and ventilatory oscillations. We studied five patients who developed a sustained non-obstructive PB pattern during a 20 min laboratory recording. The time course of the fractal dimension of the EEG signal (HFD) was estimated dividing this signal into 2 s segments, with a 1.5 s overlap and computing for each EEG segment the fractal dimension using the Higuchi's algorithm. From the lung volume signal, an instantaneous minute ventilation (IMV) signal was also computed. The relationship between IMV and HFD was assessed by bivariate spectral analysis, computing the magnitude square coherence function (MSC). In four patients the value of the MSC was very high, ranging from 0.75 to 0.91, while in one patient the value was only 0.29. Our results suggest that in patients with PB, rhythmic changes in the EEG signal are very common and, when present, they are associated with ventilatory oscillations. We have also demonstrated that such oscillations can be detected very effectively by a technique based on nonlinear methods.

Original languageEnglish
Title of host publicationProceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
Pages6276-6279
Number of pages4
DOIs
Publication statusPublished - 2009
Event31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 - Minneapolis, MN, United States
Duration: Sep 2 2009Sep 6 2009

Other

Other31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
CountryUnited States
CityMinneapolis, MN
Period9/2/099/6/09

ASJC Scopus subject areas

  • Cell Biology
  • Developmental Biology
  • Biomedical Engineering
  • Medicine(all)

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    Maestri, R., La Rovere, M. T., Robbi, E., & Pinna, G. D. (2009). Relationship between ventilatory oscillations and fractal dimension of the EEG during daytime periodic breathing in heart failure patients. In Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 (pp. 6276-6279). [5332385] https://doi.org/10.1109/IEMBS.2009.5332385