TY - JOUR
T1 - Relationship of job satisfaction, psychological distress and stress-related biological parameters among healthy nurses
T2 - A longitudinal study
AU - Amati, Monica
AU - Tomasetti, Marco
AU - Ciuccarelli, Marida
AU - Mariotti, Laura
AU - Tarquini, Lucia Miria
AU - Bracci, Massimo
AU - Baldassari, Maurizio
AU - Balducci, Cristian
AU - Alleva, Renata
AU - Borghi, Battista
AU - Mocchegiani, Eugenio
AU - Copertaro, Alfredo
AU - Santarelli, Lory
PY - 2010/1
Y1 - 2010/1
N2 - Objective: To examine the relationship between job satisfaction, psychological distress, psychosocial processes and stress-related biological factors, and to evaluate whether over time changes of work satisfaction could affect the immunological-inflammatory status of workers. Methods: One hundred and one nurses were enrolled at the Clinic of Occupational Medicine, Polytechnic University of Marche, Ancona, Italy. Perceived job satisfaction, psychological distress, and social support were assessed every 4 mo over a 1-yr period using 4 self-reported questionnaires. T lymphocytes CD3, CD4+, CD8+, CD8+-CD57+, B lymphocyte CD19+, NK cells CD56+, and NK cell activity were determined. Results: Job satisfaction was associated with reduced psychological distress and was characterized by low cell numbers of CD8+ suppressor T cells, CD8+-CD57+ related to changes in the immunological-inflammatory variables. Subjects who increased their job satisfaction showed a reduced psychological stress associated with reduced number of CD8+-CD57+ activated T cells and inflammatory cytokines. Conclusions: Job (dis)satisfaction is related with psychological mechanisms in stress affecting cellular immune function.
AB - Objective: To examine the relationship between job satisfaction, psychological distress, psychosocial processes and stress-related biological factors, and to evaluate whether over time changes of work satisfaction could affect the immunological-inflammatory status of workers. Methods: One hundred and one nurses were enrolled at the Clinic of Occupational Medicine, Polytechnic University of Marche, Ancona, Italy. Perceived job satisfaction, psychological distress, and social support were assessed every 4 mo over a 1-yr period using 4 self-reported questionnaires. T lymphocytes CD3, CD4+, CD8+, CD8+-CD57+, B lymphocyte CD19+, NK cells CD56+, and NK cell activity were determined. Results: Job satisfaction was associated with reduced psychological distress and was characterized by low cell numbers of CD8+ suppressor T cells, CD8+-CD57+ related to changes in the immunological-inflammatory variables. Subjects who increased their job satisfaction showed a reduced psychological stress associated with reduced number of CD8+-CD57+ activated T cells and inflammatory cytokines. Conclusions: Job (dis)satisfaction is related with psychological mechanisms in stress affecting cellular immune function.
KW - Cytokines
KW - Immunological parameters
KW - Job satisfaction
KW - Lymphocytes
KW - Nurses
KW - Psychological stress
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U2 - 10.1539/joh.L9042
DO - 10.1539/joh.L9042
M3 - Article
C2 - 20032591
AN - SCOPUS:77952307192
VL - 52
SP - 31
EP - 38
JO - Journal of Occupational Health
JF - Journal of Occupational Health
SN - 1341-9145
IS - 1
ER -