Relationships between left ventricular mass and clinical, biohumoral and hemodynamic parameters in human hypertension

M. Volpe, B. Trimarco, A. Mele, A. Cuocolo, N. De Luca, B. Ricciardelli, M. Condorelli

Research output: Contribution to journalArticle

Abstract

The relationships between left ventricular mass (LVM), assessed by echocardiography, and several biohumoral and hemodynamic parameters were studied in 63 mild or moderate hypertensive patients and in an age-matched group of 23 normotensive subjects. In hypertensive patients, but not in normotensives, LVM index was significantly correlated with beta-adrenoceptor responsiveness, as evaluated by the chronotropic response to isoproterenol (CD25) (r = 0.525, p 25 and the catecholamine urinary output were significantly higher in the hypertensives as compared with the normotensive subjects. Moreover, left ventricular wall thickness (septum + posterior wall) was significantly correlated with CD25 and urinary catecholamines only in hypertensive patients. No significant correlation was found between LVM or wall thickness and body surface area, age, blood pressure, heart rate, cardiac output, total peripheral resistance and left ventricular systolic wall stress, whereas CD25 was correlated with urinary catecholamines only in hypertensive patients (r = 0.606, p

Original languageEnglish
Pages (from-to)1-12
Number of pages12
JournalCardiology
Volume71
Issue number1
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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    Volpe, M., Trimarco, B., Mele, A., Cuocolo, A., De Luca, N., Ricciardelli, B., & Condorelli, M. (1984). Relationships between left ventricular mass and clinical, biohumoral and hemodynamic parameters in human hypertension. Cardiology, 71(1), 1-12.