Abstract
Several metabolic (HbA1, HDL-C, triglycerides) and hemostatic (VIIIR:Ag, VIII:C, B-TG) variables were investigated in 35 non-obese, insulin-dependent diabetics without clinically evident vascular complications. B-TG was high but did not correlate with other metabolic and hemostatic parameters, suggesting that elevated B-TG in diabetes might be an expression of in vitro platelet activation. VIIIR:Ag and the ratio of VIIIR:Ag to VIII:C were markedly increased. There was a significant correlation of the HbA1 and HDL-C levels with VIIIR: Ag, indicating that VIIIR:Ag is another reflection of metabolic control in diabetes. Additional pathogenic mechanisms, however, appear to be involved in causing the changes in VIIIR: Ag in diabetes.
Original language | English |
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Pages (from-to) | 199-206 |
Number of pages | 8 |
Journal | Acta Diabetologica Latina |
Volume | 18 |
Issue number | 3 |
DOIs | |
Publication status | Published - Jul 1981 |
Keywords
- Beta-thromboglobulin
- Diabetic complications
- Diabetic control
- Factor-VIII procoagulant activity
- Factor-VIII related antigen
- Hemoglobin A
- High density lipoprotein-cholesterol
- Triglycerides
ASJC Scopus subject areas
- Internal Medicine
- Endocrinology, Diabetes and Metabolism
- Endocrinology