Abstract
Objective: To investigate the reliability of colposcopy during pregnancy and to evaluate the concordance between colposcopic patterns and histopathological findings in these women. Study design: Multicenter observational study of women diagnosed with an abnormal cervical cytology, who subsequently underwent a colposcopic evaluation with cervical biopsy during pregnancy. The “colpo-histopathological concordance” was evaluated. The “colposcopic overestimation and underestimation” were evaluated as well. Results: 69 women, fulfilling the study inclusion/exclusion criteria, constituted the study cohort. Among them, on colposcopic examination, 14 women (20.3%) showed “grade I abnormal colposcopic findings” 52 (75.4%) showed “grade II abnormal colposcopic findings” and the remaining 3 women (4.3%) had a “suspicious for invasion” colposcopy. The histopathological diagnosis showed 2 negative biopsies, 12 (17.4%) cases of CIN1, 50 (72.5%) cases of CIN2 and 5 (7.2%) cases of invasive cervical cancer. We found a colposcopic overestimation in 10 cases (14.5%), underestimation in 12 cases (17.4%), and a concordance in 47 cases (68.1%). A better reliability of colposcopy in women in the firsts two trimesters and in particular in women ≤20 weeks pregnant was found (Cohen's weighted kappa: 0.65). Conclusions: When performed by gynecologists with expertise, colposcopy is a reliable diagnostic tool, even during pregnancy. Whenever possible, a colposcopic evaluation during the first half of pregnancy is preferable.
| Original language | English |
|---|---|
| Pages (from-to) | 76-81 |
| Number of pages | 6 |
| Journal | European Journal of Obstetrics Gynecology and Reproductive Biology |
| Volume | 229 |
| DOIs | |
| Publication status | Published - Oct 1 2018 |
Fingerprint
Keywords
- Cervical intraepithelial lesions
- CIN
- Colposcopy
- Pregnancy
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynaecology
Cite this
Reliability of colposcopy during pregnancy. / Ciavattini, Andrea; Serri, Matteo; Di Giuseppe, Jacopo; Liverani, Carlo A.; Fallani, Maria G.; Tsiroglou, Dimitrios; Papiccio, Maria; Dellin Carpini, Giovanni; Pieralli, Annalisa; Clemente, Nicolò; Sopracordevole, Francesco.
In: European Journal of Obstetrics Gynecology and Reproductive Biology, Vol. 229, 01.10.2018, p. 76-81.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Reliability of colposcopy during pregnancy
AU - Ciavattini, Andrea
AU - Serri, Matteo
AU - Di Giuseppe, Jacopo
AU - Liverani, Carlo A.
AU - Fallani, Maria G.
AU - Tsiroglou, Dimitrios
AU - Papiccio, Maria
AU - Dellin Carpini, Giovanni
AU - Pieralli, Annalisa
AU - Clemente, Nicolò
AU - Sopracordevole, Francesco
PY - 2018/10/1
Y1 - 2018/10/1
N2 - Objective: To investigate the reliability of colposcopy during pregnancy and to evaluate the concordance between colposcopic patterns and histopathological findings in these women. Study design: Multicenter observational study of women diagnosed with an abnormal cervical cytology, who subsequently underwent a colposcopic evaluation with cervical biopsy during pregnancy. The “colpo-histopathological concordance” was evaluated. The “colposcopic overestimation and underestimation” were evaluated as well. Results: 69 women, fulfilling the study inclusion/exclusion criteria, constituted the study cohort. Among them, on colposcopic examination, 14 women (20.3%) showed “grade I abnormal colposcopic findings” 52 (75.4%) showed “grade II abnormal colposcopic findings” and the remaining 3 women (4.3%) had a “suspicious for invasion” colposcopy. The histopathological diagnosis showed 2 negative biopsies, 12 (17.4%) cases of CIN1, 50 (72.5%) cases of CIN2 and 5 (7.2%) cases of invasive cervical cancer. We found a colposcopic overestimation in 10 cases (14.5%), underestimation in 12 cases (17.4%), and a concordance in 47 cases (68.1%). A better reliability of colposcopy in women in the firsts two trimesters and in particular in women ≤20 weeks pregnant was found (Cohen's weighted kappa: 0.65). Conclusions: When performed by gynecologists with expertise, colposcopy is a reliable diagnostic tool, even during pregnancy. Whenever possible, a colposcopic evaluation during the first half of pregnancy is preferable.
AB - Objective: To investigate the reliability of colposcopy during pregnancy and to evaluate the concordance between colposcopic patterns and histopathological findings in these women. Study design: Multicenter observational study of women diagnosed with an abnormal cervical cytology, who subsequently underwent a colposcopic evaluation with cervical biopsy during pregnancy. The “colpo-histopathological concordance” was evaluated. The “colposcopic overestimation and underestimation” were evaluated as well. Results: 69 women, fulfilling the study inclusion/exclusion criteria, constituted the study cohort. Among them, on colposcopic examination, 14 women (20.3%) showed “grade I abnormal colposcopic findings” 52 (75.4%) showed “grade II abnormal colposcopic findings” and the remaining 3 women (4.3%) had a “suspicious for invasion” colposcopy. The histopathological diagnosis showed 2 negative biopsies, 12 (17.4%) cases of CIN1, 50 (72.5%) cases of CIN2 and 5 (7.2%) cases of invasive cervical cancer. We found a colposcopic overestimation in 10 cases (14.5%), underestimation in 12 cases (17.4%), and a concordance in 47 cases (68.1%). A better reliability of colposcopy in women in the firsts two trimesters and in particular in women ≤20 weeks pregnant was found (Cohen's weighted kappa: 0.65). Conclusions: When performed by gynecologists with expertise, colposcopy is a reliable diagnostic tool, even during pregnancy. Whenever possible, a colposcopic evaluation during the first half of pregnancy is preferable.
KW - Cervical intraepithelial lesions
KW - CIN
KW - Colposcopy
KW - Pregnancy
UR - http://www.scopus.com/inward/record.url?scp=85051368344&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85051368344&partnerID=8YFLogxK
U2 - 10.1016/j.ejogrb.2018.07.029
DO - 10.1016/j.ejogrb.2018.07.029
M3 - Article
AN - SCOPUS:85051368344
VL - 229
SP - 76
EP - 81
JO - European Journal of Obstetrics, Gynecology and Reproductive Biology
JF - European Journal of Obstetrics, Gynecology and Reproductive Biology
SN - 0028-2243
ER -