Abstract
Procalcitonin PCT has been proposed as an interesting marker in the diagnosis, prognosis, and response to treatment of patient with neonatal sepsis. Fifty-nine neonates 34 males and 25 females with a mean gestational age of ∼31 weeks and a mean weight of about 1750 g admitted in the Neonatal Intensive Care Unit of Cagliari Italy were evaluated in controls and in infected neonates, before and after 48 h of life. From our experience it emerges that PCT is a marker of early and late neonatal sepsis which is reliable in preterm neonates. A cut-off of 0.5 ngml starting from the third day of life appears to be capable of ensuring good test sensitivity and specificity.
| Original language | English |
|---|---|
| Pages (from-to) | 96-101 |
| Number of pages | 6 |
| Journal | Journal of Maternal-Fetal and Neonatal Medicine |
| Volume | 22 |
| Issue number | SUPPL. 3 |
| DOIs | |
| Publication status | Published - 2009 |
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Keywords
- Acute-phase markers
- Infection
- Neonatal sepsis
- Preterm newborns
- Procalcitonin
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Obstetrics and Gynaecology
Cite this
Reliability of procalcitonin in neonatology. Experience in 59 preterm newborns. / Spada, Serena; Cuccu, Antonella; Mussap, Michele; Testa, Marcella; Puddu, Melania; Pisu, Cinzia; Burrai, Pietrina; Fanos, Vassilios.
In: Journal of Maternal-Fetal and Neonatal Medicine, Vol. 22, No. SUPPL. 3, 2009, p. 96-101.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Reliability of procalcitonin in neonatology. Experience in 59 preterm newborns
AU - Spada, Serena
AU - Cuccu, Antonella
AU - Mussap, Michele
AU - Testa, Marcella
AU - Puddu, Melania
AU - Pisu, Cinzia
AU - Burrai, Pietrina
AU - Fanos, Vassilios
PY - 2009
Y1 - 2009
N2 - Procalcitonin PCT has been proposed as an interesting marker in the diagnosis, prognosis, and response to treatment of patient with neonatal sepsis. Fifty-nine neonates 34 males and 25 females with a mean gestational age of ∼31 weeks and a mean weight of about 1750 g admitted in the Neonatal Intensive Care Unit of Cagliari Italy were evaluated in controls and in infected neonates, before and after 48 h of life. From our experience it emerges that PCT is a marker of early and late neonatal sepsis which is reliable in preterm neonates. A cut-off of 0.5 ngml starting from the third day of life appears to be capable of ensuring good test sensitivity and specificity.
AB - Procalcitonin PCT has been proposed as an interesting marker in the diagnosis, prognosis, and response to treatment of patient with neonatal sepsis. Fifty-nine neonates 34 males and 25 females with a mean gestational age of ∼31 weeks and a mean weight of about 1750 g admitted in the Neonatal Intensive Care Unit of Cagliari Italy were evaluated in controls and in infected neonates, before and after 48 h of life. From our experience it emerges that PCT is a marker of early and late neonatal sepsis which is reliable in preterm neonates. A cut-off of 0.5 ngml starting from the third day of life appears to be capable of ensuring good test sensitivity and specificity.
KW - Acute-phase markers
KW - Infection
KW - Neonatal sepsis
KW - Preterm newborns
KW - Procalcitonin
UR - http://www.scopus.com/inward/record.url?scp=70449449675&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=70449449675&partnerID=8YFLogxK
U2 - 10.1080/14767050903195450
DO - 10.1080/14767050903195450
M3 - Article
C2 - 19925368
AN - SCOPUS:70449449675
VL - 22
SP - 96
EP - 101
JO - Journal of Maternal-Fetal and Neonatal Medicine
JF - Journal of Maternal-Fetal and Neonatal Medicine
SN - 1476-7058
IS - SUPPL. 3
ER -