Reliability of procalcitonin in neonatology. Experience in 59 preterm newborns

Serena Spada, Antonella Cuccu, Michele Mussap, Marcella Testa, Melania Puddu, Cinzia Pisu, Pietrina Burrai, Vassilios Fanos

Research output: Contribution to journalArticle

Abstract

Procalcitonin PCT has been proposed as an interesting marker in the diagnosis, prognosis, and response to treatment of patient with neonatal sepsis. Fifty-nine neonates 34 males and 25 females with a mean gestational age of ∼31 weeks and a mean weight of about 1750 g admitted in the Neonatal Intensive Care Unit of Cagliari Italy were evaluated in controls and in infected neonates, before and after 48 h of life. From our experience it emerges that PCT is a marker of early and late neonatal sepsis which is reliable in preterm neonates. A cut-off of 0.5 ngml starting from the third day of life appears to be capable of ensuring good test sensitivity and specificity.

Original languageEnglish
Pages (from-to)96-101
Number of pages6
JournalJournal of Maternal-Fetal and Neonatal Medicine
Volume22
Issue numberSUPPL. 3
DOIs
Publication statusPublished - 2009

Fingerprint

Neonatology
Calcitonin
Newborn Infant
Neonatal Intensive Care Units
Italy
Gestational Age
Weights and Measures
Sensitivity and Specificity
Neonatal Sepsis
Therapeutics

Keywords

  • Acute-phase markers
  • Infection
  • Neonatal sepsis
  • Preterm newborns
  • Procalcitonin

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynaecology

Cite this

Spada, S., Cuccu, A., Mussap, M., Testa, M., Puddu, M., Pisu, C., ... Fanos, V. (2009). Reliability of procalcitonin in neonatology. Experience in 59 preterm newborns. Journal of Maternal-Fetal and Neonatal Medicine, 22(SUPPL. 3), 96-101. https://doi.org/10.1080/14767050903195450

Reliability of procalcitonin in neonatology. Experience in 59 preterm newborns. / Spada, Serena; Cuccu, Antonella; Mussap, Michele; Testa, Marcella; Puddu, Melania; Pisu, Cinzia; Burrai, Pietrina; Fanos, Vassilios.

In: Journal of Maternal-Fetal and Neonatal Medicine, Vol. 22, No. SUPPL. 3, 2009, p. 96-101.

Research output: Contribution to journalArticle

Spada, S, Cuccu, A, Mussap, M, Testa, M, Puddu, M, Pisu, C, Burrai, P & Fanos, V 2009, 'Reliability of procalcitonin in neonatology. Experience in 59 preterm newborns', Journal of Maternal-Fetal and Neonatal Medicine, vol. 22, no. SUPPL. 3, pp. 96-101. https://doi.org/10.1080/14767050903195450
Spada, Serena ; Cuccu, Antonella ; Mussap, Michele ; Testa, Marcella ; Puddu, Melania ; Pisu, Cinzia ; Burrai, Pietrina ; Fanos, Vassilios. / Reliability of procalcitonin in neonatology. Experience in 59 preterm newborns. In: Journal of Maternal-Fetal and Neonatal Medicine. 2009 ; Vol. 22, No. SUPPL. 3. pp. 96-101.
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