Reliability of procalcitonin in neonatology. Experience in 59 preterm newborns

Serena Spada; Antonella Cuccu; Michele Mussap; Marcella Testa; Melania Puddu; Cinzia Pisu; Pietrina Burrai; Vassilios Fanos

doi:10.1080/14767050903195450

Reliability of procalcitonin in neonatology. Experience in 59 preterm newborns

Serena Spada, Antonella Cuccu, Michele Mussap, Marcella Testa, Melania Puddu, Cinzia Pisu, Pietrina Burrai, Vassilios Fanos

A.O.U. San Martino - IST, Istituto Nazionale Ricerca sul Cancro (GENOVA)

Research output: Contribution to journal › Article › peer-review

Abstract

Procalcitonin PCT has been proposed as an interesting marker in the diagnosis, prognosis, and response to treatment of patient with neonatal sepsis. Fifty-nine neonates 34 males and 25 females with a mean gestational age of ∼31 weeks and a mean weight of about 1750 g admitted in the Neonatal Intensive Care Unit of Cagliari Italy were evaluated in controls and in infected neonates, before and after 48 h of life. From our experience it emerges that PCT is a marker of early and late neonatal sepsis which is reliable in preterm neonates. A cut-off of 0.5 ngml starting from the third day of life appears to be capable of ensuring good test sensitivity and specificity.

Original language	English
Pages (from-to)	96-101
Number of pages	6
Journal	Journal of Maternal-Fetal and Neonatal Medicine
Volume	22
Issue number	SUPPL. 3
DOIs	https://doi.org/10.1080/14767050903195450
Publication status	Published - 2009

Keywords

Acute-phase markers
Infection
Neonatal sepsis
Preterm newborns
Procalcitonin

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynaecology

Access to Document

10.1080/14767050903195450

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Reliability of procalcitonin in neonatology. Experience in 59 preterm newborns. / Spada, Serena; Cuccu, Antonella; Mussap, Michele; Testa, Marcella; Puddu, Melania; Pisu, Cinzia; Burrai, Pietrina; Fanos, Vassilios.

In: Journal of Maternal-Fetal and Neonatal Medicine, Vol. 22, No. SUPPL. 3, 2009, p. 96-101.

Research output: Contribution to journal › Article › peer-review

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