Abstract
The objective of this study is to evaluate the effect of cryopreservation at different storage temperatures on urinary 6-sulfatoxymelatonin (aMT6s) concentration. Overnight urine from 28 postmenopausal women participating in the ORDET cohort study was filtered and separated into 6 mL aliquots. Urine samples were stored at -80°C and at -30°C for an average of 14 years. Urinary aMT6s concentration was assessed using a competitive immunoassay. Mean aMT6s values of samples stored at -30°C were systematically lower than those of samples stored at -80°C (10.7 ng/mL versus 15.8 ng/mL, p
Original language | English |
---|---|
Pages (from-to) | 242-245 |
Number of pages | 4 |
Journal | International Journal of Biological Markers |
Volume | 21 |
Issue number | 4 |
Publication status | Published - Oct 2006 |
Keywords
- 6-Sulfatoxymelatonin
- Biomarker
- Breast cancer
- Cryopreservation
- Storage temperature
ASJC Scopus subject areas
- Immunology
- Biochemistry