Remifentanil conscious sedation during regional anaesthesia for carotid endarterectomy: Rationale and safety

M. M. Marrocco-Trischitta, G. Bandiera, S. Camilli, F. Stillo, C. Cirielli, P. Guerrini

Research output: Contribution to journalArticlepeer-review


Objectives: to prospectively evaluate the safety and efficacy of remifentanil during regional anaesthesia for carotid endarterectomy. Methods: twenty-eight consecutive patients underwent carotid endarterectomy with combined superficial and deep cervical plexus block supplemented with continuous intravenous 0.04 μg·kg-1·min-1 remifentanil infusion. Depth of sedation was monitored using the Observer's Assessment of Alertness/Sedation Scale (OAA/S). The degree of pain, discomfort and anxiety was self-assessed by the patients using a horizontal visual analogue scale. Results: all patients experienced adequate comfort and analgesia. No local anaesthetic supplementation was necessary. No patient had a OAA/S score lower than 4 (with 5=awake/alert to 1=asleep). Respiratory depression did not occur. Selective shunting was required in four cases. No patient was converted to general anaesthesia. There were no permanent neurological deficits, cardiopulmonary complications or deaths. Conclusion: remifentanil as a supplement to regional aneasthesia for carotid endarterectomy, provides comfort and analgesia without hampering mental status evaluation.

Original languageEnglish
Pages (from-to)405-409
Number of pages5
JournalEuropean Journal of Vascular and Endovascular Surgery
Issue number5
Publication statusPublished - 2001


  • Carotid endarterectomy
  • Conscious sedation
  • Regional anaesthesia
  • Remifentanil

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging
  • Surgery


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