Remission of Behçet's disease and keratoconjunctivitis sicca in an HIV-infected patient treated with HAART

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9 Citations (Scopus)

Abstract

A 34-year-old woman presented with a 10-year history of recurrent oral and genital ulcerations and recurrent episodes of bilateral conjunctivitis associated with HIV infection. A diagnosis of Behçet's disease (BD) in association with keratoconjunctivitis sicca (KCS) was made after exclusion of other viral and autoimmune diseases according to the international criteria for BD. This is the first reported case of a combination of BD and KCS in a patient with HIV infection in which a complete resolution was observed as a result of successful highly active antiretroviral therapy. The likelihood that a direct viral effect or HIV-induced autoimmune mechanisms act in the pathogenesis of both BD and KCS in HIV-infected patients is discussed.

Original languageEnglish
Pages (from-to)139-140
Number of pages2
JournalInternational Journal of STD and AIDS
Volume15
Issue number2
DOIs
Publication statusPublished - Feb 2004

Fingerprint

Keratoconjunctivitis Sicca
Highly Active Antiretroviral Therapy
HIV
HIV Infections
Conjunctivitis
Virus Diseases
Autoimmune Diseases
Interviews

Keywords

  • Behçet's disease
  • HAART
  • HIV infection
  • Keratoconjunctivitis

ASJC Scopus subject areas

  • Immunology
  • Dermatology
  • Microbiology (medical)
  • Public Health, Environmental and Occupational Health

Cite this

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title = "Remission of Beh{\cc}et's disease and keratoconjunctivitis sicca in an HIV-infected patient treated with HAART",
abstract = "A 34-year-old woman presented with a 10-year history of recurrent oral and genital ulcerations and recurrent episodes of bilateral conjunctivitis associated with HIV infection. A diagnosis of Beh{\cc}et's disease (BD) in association with keratoconjunctivitis sicca (KCS) was made after exclusion of other viral and autoimmune diseases according to the international criteria for BD. This is the first reported case of a combination of BD and KCS in a patient with HIV infection in which a complete resolution was observed as a result of successful highly active antiretroviral therapy. The likelihood that a direct viral effect or HIV-induced autoimmune mechanisms act in the pathogenesis of both BD and KCS in HIV-infected patients is discussed.",
keywords = "Beh{\cc}et's disease, HAART, HIV infection, Keratoconjunctivitis",
author = "S. Cicalini and B. Gigli and F. Palmieri and E. Boumis and N. Froio and N. Petrosillo",
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T1 - Remission of Behçet's disease and keratoconjunctivitis sicca in an HIV-infected patient treated with HAART

AU - Cicalini, S.

AU - Gigli, B.

AU - Palmieri, F.

AU - Boumis, E.

AU - Froio, N.

AU - Petrosillo, N.

PY - 2004/2

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N2 - A 34-year-old woman presented with a 10-year history of recurrent oral and genital ulcerations and recurrent episodes of bilateral conjunctivitis associated with HIV infection. A diagnosis of Behçet's disease (BD) in association with keratoconjunctivitis sicca (KCS) was made after exclusion of other viral and autoimmune diseases according to the international criteria for BD. This is the first reported case of a combination of BD and KCS in a patient with HIV infection in which a complete resolution was observed as a result of successful highly active antiretroviral therapy. The likelihood that a direct viral effect or HIV-induced autoimmune mechanisms act in the pathogenesis of both BD and KCS in HIV-infected patients is discussed.

AB - A 34-year-old woman presented with a 10-year history of recurrent oral and genital ulcerations and recurrent episodes of bilateral conjunctivitis associated with HIV infection. A diagnosis of Behçet's disease (BD) in association with keratoconjunctivitis sicca (KCS) was made after exclusion of other viral and autoimmune diseases according to the international criteria for BD. This is the first reported case of a combination of BD and KCS in a patient with HIV infection in which a complete resolution was observed as a result of successful highly active antiretroviral therapy. The likelihood that a direct viral effect or HIV-induced autoimmune mechanisms act in the pathogenesis of both BD and KCS in HIV-infected patients is discussed.

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KW - HAART

KW - HIV infection

KW - Keratoconjunctivitis

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