Renal arterial stenosis: Prospective comparison of color Doppler US and breath-hold, three-dimensional, dynamic, gadolinium-enhanced MR angiography

Francesco De Cobelli, Massimo Venturini, Angelo Vanzulli, Sandro Sironi, Marco Salvioni, Enzo Angeli, Paola Scifo, Maria Paola Garancini, Rita Quartagno, Giuseppe Bianchi, Alessandro Del Maschio

Research output: Contribution to journalArticle

Abstract

PURPOSE: To compare color Doppler ultrasonography (US) with fast, breath-hold, three-dimensional, gadolinium-enhanced magnetic resonance (MR) angiography in detecting renal arterial stenosis. MATERIALS AND METHODS: Forty-five patients with clinical suspicion of renovascular disease were prospectively examined with intra- and extrarenal color Doppler US and breath-hold, gadolinium-enhanced MR angiography. Digital subtraction arteriography (DSA) was the standard of reference in all patients for the number of renal arteries and degree of stenosis. RESULTS: DSA depicted 103 arteries and 52 stenoses. Color Doppler US was nondiagnostic in two examinations. Significantly more of 13 accessory renal arteries were detected with MR angiography (n = 12) than with color Doppler US (n = 3; P <.05). For assessing all stenoses, the sensitivity and accuracy were 94% and 91%, respectively, for MR angiography and 71% and 76%, respectively, for US (P <.05). The sensitivity was higher for MR angiography (100%) than for US (79%; P <.05) in diagnosing stenoses with at least 50% narrowing. The specificity accuracy, and negative predictive value in diagnosing stenoses of at least 50% narrowing were 93%, 95%, and 100% for MR angiography and 93%, 89%, and 90% for US. CONCLUSION: Breath-hold, gadolinium-enhanced MR angiography is superior to color Doppler US in accessory renal artery detection. Although the specificity of MR angiography is similar to that of color Doppler US, MR angiography has a better sensitivity and negative predictive value in depicting renal arterial stenoses.

Original languageEnglish
Pages (from-to)373-380
Number of pages8
JournalRadiology
Volume214
Issue number2
Publication statusPublished - Feb 2000

Keywords

  • Magnetic resonance (MR), comparative studies
  • Renal arteries, MR
  • Renal arteries, stenosis or obstruction
  • Renal arteries, US
  • Ultrasound (US), comparative studies

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

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    De Cobelli, F., Venturini, M., Vanzulli, A., Sironi, S., Salvioni, M., Angeli, E., Scifo, P., Garancini, M. P., Quartagno, R., Bianchi, G., & Del Maschio, A. (2000). Renal arterial stenosis: Prospective comparison of color Doppler US and breath-hold, three-dimensional, dynamic, gadolinium-enhanced MR angiography. Radiology, 214(2), 373-380.