Renal arterial stenosis: Prospective comparison of color Doppler US and breath-hold, three-dimensional, dynamic, gadolinium-enhanced MR angiography

Francesco De Cobelli, Massimo Venturini, Angelo Vanzulli, Sandro Sironi, Marco Salvioni, Enzo Angeli, Paola Scifo, Maria Paola Garancini, Rita Quartagno, Giuseppe Bianchi, Alessandro Del Maschio

Research output: Contribution to journalArticle

108 Citations (Scopus)

Abstract

PURPOSE: To compare color Doppler ultrasonography (US) with fast, breath-hold, three-dimensional, gadolinium-enhanced magnetic resonance (MR) angiography in detecting renal arterial stenosis. MATERIALS AND METHODS: Forty-five patients with clinical suspicion of renovascular disease were prospectively examined with intra- and extrarenal color Doppler US and breath-hold, gadolinium-enhanced MR angiography. Digital subtraction arteriography (DSA) was the standard of reference in all patients for the number of renal arteries and degree of stenosis. RESULTS: DSA depicted 103 arteries and 52 stenoses. Color Doppler US was nondiagnostic in two examinations. Significantly more of 13 accessory renal arteries were detected with MR angiography (n = 12) than with color Doppler US (n = 3; P <.05). For assessing all stenoses, the sensitivity and accuracy were 94% and 91%, respectively, for MR angiography and 71% and 76%, respectively, for US (P <.05). The sensitivity was higher for MR angiography (100%) than for US (79%; P <.05) in diagnosing stenoses with at least 50% narrowing. The specificity accuracy, and negative predictive value in diagnosing stenoses of at least 50% narrowing were 93%, 95%, and 100% for MR angiography and 93%, 89%, and 90% for US. CONCLUSION: Breath-hold, gadolinium-enhanced MR angiography is superior to color Doppler US in accessory renal artery detection. Although the specificity of MR angiography is similar to that of color Doppler US, MR angiography has a better sensitivity and negative predictive value in depicting renal arterial stenoses.

Original languageEnglish
Pages (from-to)373-380
Number of pages8
JournalRadiology
Volume214
Issue number2
Publication statusPublished - Feb 2000

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Doppler Color Ultrasonography
Magnetic Resonance Angiography
Gadolinium
Pathologic Constriction
Kidney
Ultrasonography
Renal Artery
Angiography
Renal Artery Obstruction
Arteries

Keywords

  • Magnetic resonance (MR), comparative studies
  • Renal arteries, MR
  • Renal arteries, stenosis or obstruction
  • Renal arteries, US
  • Ultrasound (US), comparative studies

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Renal arterial stenosis : Prospective comparison of color Doppler US and breath-hold, three-dimensional, dynamic, gadolinium-enhanced MR angiography. / De Cobelli, Francesco; Venturini, Massimo; Vanzulli, Angelo; Sironi, Sandro; Salvioni, Marco; Angeli, Enzo; Scifo, Paola; Garancini, Maria Paola; Quartagno, Rita; Bianchi, Giuseppe; Del Maschio, Alessandro.

In: Radiology, Vol. 214, No. 2, 02.2000, p. 373-380.

Research output: Contribution to journalArticle

De Cobelli, F, Venturini, M, Vanzulli, A, Sironi, S, Salvioni, M, Angeli, E, Scifo, P, Garancini, MP, Quartagno, R, Bianchi, G & Del Maschio, A 2000, 'Renal arterial stenosis: Prospective comparison of color Doppler US and breath-hold, three-dimensional, dynamic, gadolinium-enhanced MR angiography', Radiology, vol. 214, no. 2, pp. 373-380.
De Cobelli, Francesco ; Venturini, Massimo ; Vanzulli, Angelo ; Sironi, Sandro ; Salvioni, Marco ; Angeli, Enzo ; Scifo, Paola ; Garancini, Maria Paola ; Quartagno, Rita ; Bianchi, Giuseppe ; Del Maschio, Alessandro. / Renal arterial stenosis : Prospective comparison of color Doppler US and breath-hold, three-dimensional, dynamic, gadolinium-enhanced MR angiography. In: Radiology. 2000 ; Vol. 214, No. 2. pp. 373-380.
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abstract = "PURPOSE: To compare color Doppler ultrasonography (US) with fast, breath-hold, three-dimensional, gadolinium-enhanced magnetic resonance (MR) angiography in detecting renal arterial stenosis. MATERIALS AND METHODS: Forty-five patients with clinical suspicion of renovascular disease were prospectively examined with intra- and extrarenal color Doppler US and breath-hold, gadolinium-enhanced MR angiography. Digital subtraction arteriography (DSA) was the standard of reference in all patients for the number of renal arteries and degree of stenosis. RESULTS: DSA depicted 103 arteries and 52 stenoses. Color Doppler US was nondiagnostic in two examinations. Significantly more of 13 accessory renal arteries were detected with MR angiography (n = 12) than with color Doppler US (n = 3; P <.05). For assessing all stenoses, the sensitivity and accuracy were 94{\%} and 91{\%}, respectively, for MR angiography and 71{\%} and 76{\%}, respectively, for US (P <.05). The sensitivity was higher for MR angiography (100{\%}) than for US (79{\%}; P <.05) in diagnosing stenoses with at least 50{\%} narrowing. The specificity accuracy, and negative predictive value in diagnosing stenoses of at least 50{\%} narrowing were 93{\%}, 95{\%}, and 100{\%} for MR angiography and 93{\%}, 89{\%}, and 90{\%} for US. CONCLUSION: Breath-hold, gadolinium-enhanced MR angiography is superior to color Doppler US in accessory renal artery detection. Although the specificity of MR angiography is similar to that of color Doppler US, MR angiography has a better sensitivity and negative predictive value in depicting renal arterial stenoses.",
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T2 - Prospective comparison of color Doppler US and breath-hold, three-dimensional, dynamic, gadolinium-enhanced MR angiography

AU - De Cobelli, Francesco

AU - Venturini, Massimo

AU - Vanzulli, Angelo

AU - Sironi, Sandro

AU - Salvioni, Marco

AU - Angeli, Enzo

AU - Scifo, Paola

AU - Garancini, Maria Paola

AU - Quartagno, Rita

AU - Bianchi, Giuseppe

AU - Del Maschio, Alessandro

PY - 2000/2

Y1 - 2000/2

N2 - PURPOSE: To compare color Doppler ultrasonography (US) with fast, breath-hold, three-dimensional, gadolinium-enhanced magnetic resonance (MR) angiography in detecting renal arterial stenosis. MATERIALS AND METHODS: Forty-five patients with clinical suspicion of renovascular disease were prospectively examined with intra- and extrarenal color Doppler US and breath-hold, gadolinium-enhanced MR angiography. Digital subtraction arteriography (DSA) was the standard of reference in all patients for the number of renal arteries and degree of stenosis. RESULTS: DSA depicted 103 arteries and 52 stenoses. Color Doppler US was nondiagnostic in two examinations. Significantly more of 13 accessory renal arteries were detected with MR angiography (n = 12) than with color Doppler US (n = 3; P <.05). For assessing all stenoses, the sensitivity and accuracy were 94% and 91%, respectively, for MR angiography and 71% and 76%, respectively, for US (P <.05). The sensitivity was higher for MR angiography (100%) than for US (79%; P <.05) in diagnosing stenoses with at least 50% narrowing. The specificity accuracy, and negative predictive value in diagnosing stenoses of at least 50% narrowing were 93%, 95%, and 100% for MR angiography and 93%, 89%, and 90% for US. CONCLUSION: Breath-hold, gadolinium-enhanced MR angiography is superior to color Doppler US in accessory renal artery detection. Although the specificity of MR angiography is similar to that of color Doppler US, MR angiography has a better sensitivity and negative predictive value in depicting renal arterial stenoses.

AB - PURPOSE: To compare color Doppler ultrasonography (US) with fast, breath-hold, three-dimensional, gadolinium-enhanced magnetic resonance (MR) angiography in detecting renal arterial stenosis. MATERIALS AND METHODS: Forty-five patients with clinical suspicion of renovascular disease were prospectively examined with intra- and extrarenal color Doppler US and breath-hold, gadolinium-enhanced MR angiography. Digital subtraction arteriography (DSA) was the standard of reference in all patients for the number of renal arteries and degree of stenosis. RESULTS: DSA depicted 103 arteries and 52 stenoses. Color Doppler US was nondiagnostic in two examinations. Significantly more of 13 accessory renal arteries were detected with MR angiography (n = 12) than with color Doppler US (n = 3; P <.05). For assessing all stenoses, the sensitivity and accuracy were 94% and 91%, respectively, for MR angiography and 71% and 76%, respectively, for US (P <.05). The sensitivity was higher for MR angiography (100%) than for US (79%; P <.05) in diagnosing stenoses with at least 50% narrowing. The specificity accuracy, and negative predictive value in diagnosing stenoses of at least 50% narrowing were 93%, 95%, and 100% for MR angiography and 93%, 89%, and 90% for US. CONCLUSION: Breath-hold, gadolinium-enhanced MR angiography is superior to color Doppler US in accessory renal artery detection. Although the specificity of MR angiography is similar to that of color Doppler US, MR angiography has a better sensitivity and negative predictive value in depicting renal arterial stenoses.

KW - Magnetic resonance (MR), comparative studies

KW - Renal arteries, MR

KW - Renal arteries, stenosis or obstruction

KW - Renal arteries, US

KW - Ultrasound (US), comparative studies

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