Renal artery stenosis: Evaluation with breath-hold, three-dimensional, dynamic, gadolinium-enhanced versus three-dimensional, phase-contrast MR angiography

Francesco De Cobelli, Angelo Vanzulli, Sandro Sironi, Renata Mellone, Enzo Angeli, Massimo Venturini, Maria Paola Garancini, Rita Quartagno, Giuseppe Bianchi, Alessandro Del Maschio

Research output: Contribution to journalArticle

Abstract

PURPOSE: To compare breath-hold, three-dimensional, gadolinium-enhanced magnetic resonance (MR) angiography with three-dimensional, phase-contrast MR angiography in the evaluation of renal artery stenosis. MATERIALS AND METHODS: Fifty-five consecutive adult patients with clinical suspicion of renovascular disease were prospectively examined with three-dimensional, phase-contrast MR angiography and breath hold, three-dimensional MR angiography with injection of a standard dose of gadopentetate dimeglumine to evaluate the number of renal arteries and the presence and degree of stenosis. The standard of reference was intraarterial digital subtraction angiography. RESULTS: Gadolinium-enhanced MR angiography depicted all 105 main renal arteries, whereas phase-contrast MR angiography depicted 104. The number of accessory renal arteries depicted was significantly higher with gadolinium-enhanced (17 of 18) than with phase-contrast (11 of 18) studies (P = .04). Both techniques depicted 27 of the 29 stenoses (sensitivity, 93%; P > .05). Sensitivities, specificities, and accuracies in the diagnosis of hemodynamically significant stenosis (>50% narrowing) were, respectively, 94%, 96%, and 96% for phase-contrast and 100%, 97%, and 98% for gadolinium- enhanced MR angiography (P > .05). CONCLUSION: Gadolinium-enhanced MR angiography is superior to phase-contrast MR angiography in accessory renal artery depiction. No statistically significant difference in the assessment of stenosis has been found between the two techniques.

Original languageEnglish
Pages (from-to)689-695
Number of pages7
JournalRadiology
Volume205
Issue number3
Publication statusPublished - Dec 1997

Keywords

  • Gadolinium
  • Magnetic resonance (MR), contrast enhancement
  • Magnetic resonance (MR), phase imaging
  • Magnetic resonance (MR), three- dimensional
  • Magnetic resonance (MR), vascular studies
  • Renal arteries, MR
  • Renal arteries, stenosis or obstruction

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

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    De Cobelli, F., Vanzulli, A., Sironi, S., Mellone, R., Angeli, E., Venturini, M., Garancini, M. P., Quartagno, R., Bianchi, G., & Del Maschio, A. (1997). Renal artery stenosis: Evaluation with breath-hold, three-dimensional, dynamic, gadolinium-enhanced versus three-dimensional, phase-contrast MR angiography. Radiology, 205(3), 689-695.