Renal artery stenosis: Evaluation with breath-hold, three-dimensional, dynamic, gadolinium-enhanced versus three-dimensional, phase-contrast MR angiography

Francesco De Cobelli, Angelo Vanzulli, Sandro Sironi, Renata Mellone, Enzo Angeli, Massimo Venturini, Maria Paola Garancini, Rita Quartagno, Giuseppe Bianchi, Alessandro Del Maschio

Research output: Contribution to journalArticle

113 Citations (Scopus)

Abstract

PURPOSE: To compare breath-hold, three-dimensional, gadolinium-enhanced magnetic resonance (MR) angiography with three-dimensional, phase-contrast MR angiography in the evaluation of renal artery stenosis. MATERIALS AND METHODS: Fifty-five consecutive adult patients with clinical suspicion of renovascular disease were prospectively examined with three-dimensional, phase-contrast MR angiography and breath hold, three-dimensional MR angiography with injection of a standard dose of gadopentetate dimeglumine to evaluate the number of renal arteries and the presence and degree of stenosis. The standard of reference was intraarterial digital subtraction angiography. RESULTS: Gadolinium-enhanced MR angiography depicted all 105 main renal arteries, whereas phase-contrast MR angiography depicted 104. The number of accessory renal arteries depicted was significantly higher with gadolinium-enhanced (17 of 18) than with phase-contrast (11 of 18) studies (P = .04). Both techniques depicted 27 of the 29 stenoses (sensitivity, 93%; P > .05). Sensitivities, specificities, and accuracies in the diagnosis of hemodynamically significant stenosis (>50% narrowing) were, respectively, 94%, 96%, and 96% for phase-contrast and 100%, 97%, and 98% for gadolinium- enhanced MR angiography (P > .05). CONCLUSION: Gadolinium-enhanced MR angiography is superior to phase-contrast MR angiography in accessory renal artery depiction. No statistically significant difference in the assessment of stenosis has been found between the two techniques.

Original languageEnglish
Pages (from-to)689-695
Number of pages7
JournalRadiology
Volume205
Issue number3
Publication statusPublished - Dec 1997

Fingerprint

Renal Artery Obstruction
Magnetic Resonance Angiography
Gadolinium
Renal Artery
Pathologic Constriction
Gadolinium DTPA
Digital Subtraction Angiography
Sensitivity and Specificity
Injections

Keywords

  • Gadolinium
  • Magnetic resonance (MR), contrast enhancement
  • Magnetic resonance (MR), phase imaging
  • Magnetic resonance (MR), three- dimensional
  • Magnetic resonance (MR), vascular studies
  • Renal arteries, MR
  • Renal arteries, stenosis or obstruction

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Renal artery stenosis : Evaluation with breath-hold, three-dimensional, dynamic, gadolinium-enhanced versus three-dimensional, phase-contrast MR angiography. / De Cobelli, Francesco; Vanzulli, Angelo; Sironi, Sandro; Mellone, Renata; Angeli, Enzo; Venturini, Massimo; Garancini, Maria Paola; Quartagno, Rita; Bianchi, Giuseppe; Del Maschio, Alessandro.

In: Radiology, Vol. 205, No. 3, 12.1997, p. 689-695.

Research output: Contribution to journalArticle

De Cobelli, F, Vanzulli, A, Sironi, S, Mellone, R, Angeli, E, Venturini, M, Garancini, MP, Quartagno, R, Bianchi, G & Del Maschio, A 1997, 'Renal artery stenosis: Evaluation with breath-hold, three-dimensional, dynamic, gadolinium-enhanced versus three-dimensional, phase-contrast MR angiography', Radiology, vol. 205, no. 3, pp. 689-695.
De Cobelli, Francesco ; Vanzulli, Angelo ; Sironi, Sandro ; Mellone, Renata ; Angeli, Enzo ; Venturini, Massimo ; Garancini, Maria Paola ; Quartagno, Rita ; Bianchi, Giuseppe ; Del Maschio, Alessandro. / Renal artery stenosis : Evaluation with breath-hold, three-dimensional, dynamic, gadolinium-enhanced versus three-dimensional, phase-contrast MR angiography. In: Radiology. 1997 ; Vol. 205, No. 3. pp. 689-695.
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abstract = "PURPOSE: To compare breath-hold, three-dimensional, gadolinium-enhanced magnetic resonance (MR) angiography with three-dimensional, phase-contrast MR angiography in the evaluation of renal artery stenosis. MATERIALS AND METHODS: Fifty-five consecutive adult patients with clinical suspicion of renovascular disease were prospectively examined with three-dimensional, phase-contrast MR angiography and breath hold, three-dimensional MR angiography with injection of a standard dose of gadopentetate dimeglumine to evaluate the number of renal arteries and the presence and degree of stenosis. The standard of reference was intraarterial digital subtraction angiography. RESULTS: Gadolinium-enhanced MR angiography depicted all 105 main renal arteries, whereas phase-contrast MR angiography depicted 104. The number of accessory renal arteries depicted was significantly higher with gadolinium-enhanced (17 of 18) than with phase-contrast (11 of 18) studies (P = .04). Both techniques depicted 27 of the 29 stenoses (sensitivity, 93{\%}; P > .05). Sensitivities, specificities, and accuracies in the diagnosis of hemodynamically significant stenosis (>50{\%} narrowing) were, respectively, 94{\%}, 96{\%}, and 96{\%} for phase-contrast and 100{\%}, 97{\%}, and 98{\%} for gadolinium- enhanced MR angiography (P > .05). CONCLUSION: Gadolinium-enhanced MR angiography is superior to phase-contrast MR angiography in accessory renal artery depiction. No statistically significant difference in the assessment of stenosis has been found between the two techniques.",
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T2 - Evaluation with breath-hold, three-dimensional, dynamic, gadolinium-enhanced versus three-dimensional, phase-contrast MR angiography

AU - De Cobelli, Francesco

AU - Vanzulli, Angelo

AU - Sironi, Sandro

AU - Mellone, Renata

AU - Angeli, Enzo

AU - Venturini, Massimo

AU - Garancini, Maria Paola

AU - Quartagno, Rita

AU - Bianchi, Giuseppe

AU - Del Maschio, Alessandro

PY - 1997/12

Y1 - 1997/12

N2 - PURPOSE: To compare breath-hold, three-dimensional, gadolinium-enhanced magnetic resonance (MR) angiography with three-dimensional, phase-contrast MR angiography in the evaluation of renal artery stenosis. MATERIALS AND METHODS: Fifty-five consecutive adult patients with clinical suspicion of renovascular disease were prospectively examined with three-dimensional, phase-contrast MR angiography and breath hold, three-dimensional MR angiography with injection of a standard dose of gadopentetate dimeglumine to evaluate the number of renal arteries and the presence and degree of stenosis. The standard of reference was intraarterial digital subtraction angiography. RESULTS: Gadolinium-enhanced MR angiography depicted all 105 main renal arteries, whereas phase-contrast MR angiography depicted 104. The number of accessory renal arteries depicted was significantly higher with gadolinium-enhanced (17 of 18) than with phase-contrast (11 of 18) studies (P = .04). Both techniques depicted 27 of the 29 stenoses (sensitivity, 93%; P > .05). Sensitivities, specificities, and accuracies in the diagnosis of hemodynamically significant stenosis (>50% narrowing) were, respectively, 94%, 96%, and 96% for phase-contrast and 100%, 97%, and 98% for gadolinium- enhanced MR angiography (P > .05). CONCLUSION: Gadolinium-enhanced MR angiography is superior to phase-contrast MR angiography in accessory renal artery depiction. No statistically significant difference in the assessment of stenosis has been found between the two techniques.

AB - PURPOSE: To compare breath-hold, three-dimensional, gadolinium-enhanced magnetic resonance (MR) angiography with three-dimensional, phase-contrast MR angiography in the evaluation of renal artery stenosis. MATERIALS AND METHODS: Fifty-five consecutive adult patients with clinical suspicion of renovascular disease were prospectively examined with three-dimensional, phase-contrast MR angiography and breath hold, three-dimensional MR angiography with injection of a standard dose of gadopentetate dimeglumine to evaluate the number of renal arteries and the presence and degree of stenosis. The standard of reference was intraarterial digital subtraction angiography. RESULTS: Gadolinium-enhanced MR angiography depicted all 105 main renal arteries, whereas phase-contrast MR angiography depicted 104. The number of accessory renal arteries depicted was significantly higher with gadolinium-enhanced (17 of 18) than with phase-contrast (11 of 18) studies (P = .04). Both techniques depicted 27 of the 29 stenoses (sensitivity, 93%; P > .05). Sensitivities, specificities, and accuracies in the diagnosis of hemodynamically significant stenosis (>50% narrowing) were, respectively, 94%, 96%, and 96% for phase-contrast and 100%, 97%, and 98% for gadolinium- enhanced MR angiography (P > .05). CONCLUSION: Gadolinium-enhanced MR angiography is superior to phase-contrast MR angiography in accessory renal artery depiction. No statistically significant difference in the assessment of stenosis has been found between the two techniques.

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KW - Magnetic resonance (MR), vascular studies

KW - Renal arteries, MR

KW - Renal arteries, stenosis or obstruction

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