Renal cell carcinoma (RCC) represents 2-3% of all cancers, with the highest incidence in Western countries and particularly in Europe, where the annual increase in the incidence of this disease is 2% [1, 2]. More than 50% of RCCs are diagnosed incidentally and are asymptomatic. The classic triad of flank pain, gross hematuria, and a palpable abdominal mass is seen in very few patients (6-10%). Paraneoplastic symptoms (e.g., hypertension, weight loss, pyrexia, neuromyopathy, anemia, polycythemia, amyloidosis, elevated erythrocyte sedimentation rate, and abnormal liver function) are found in approximately 20-30% of patients with RCC and about 20-30% of all RCC patients have metastatic disease.
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)