Renal cell cancer and body size at different ages: An Italian multicenter case-control study

Luigino Dal Maso, Antonella Zucchetto, Alessandra Tavani, Maurizio Montella, Valerio Ramazzotti, Renato Talamini, Vincenzo Canzonieri, Antonio Garbeglio, Eva Negri, Annamaria Tonini, Carlo La Vecchia, Silvia Franceschi

Research output: Contribution to journalArticlepeer-review

Abstract

An increased risk of renal cell cancer (RCC) has been reported in overweight persons. The authors aimed to clarify which anthropometric measures are associated with risk of RCC and whether risk may vary according to selected variables. Between 1992 and 2004, they carried out an Italian multicenter case-control study including 767 (494 men, 273 women) incident cases of RCC and 1,534 hospital controls, frequency-matched to cases. To estimate odds ratios and 95% confidence intervals, they used conditional logistic regression matched on study center, sex, and age and adjusted for period of interview, years of education, smoking habits, and family history of kidney cancer. Using body-size measurements taken 1 year prior to diagnosis/interview, the authors found an odds ratio of 1.3 (95% confidence interval (CI): 1.0, 1.7) among obese persons (body mass index (BMI; weight (kg)/height (m)2) ≥30) versus normal-weight persons (BMI

Original languageEnglish
Pages (from-to)582-591
Number of pages10
JournalAmerican Journal of Epidemiology
Volume166
Issue number5
DOIs
Publication statusPublished - Sep 2007

Keywords

  • Body mass index
  • Body size
  • Carcinoma, renal cell
  • Case-control studies
  • Waist-hip ratio

ASJC Scopus subject areas

  • Epidemiology

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