Renal cell carcinoma with solitary toe metastasis

Sisto Perdonà, Riccardo Autorino, Luigi Gallo, Marco De Sio, Luigi Marra, Luigi Claudio, Corrado Caracò, Renato Franco, Flavio Fazzioli, Antonio Gallo

Research output: Contribution to journalArticlepeer-review


Solitary metastases to the small bones and/or to the soft tissue of the hands and feet (acrometastases) are rare. We report a case of renal cell carcinoma (RCC) with big toe metastasis revealed before the primary tumor became apparent. The best treatment for a single metastasis is always surgical excision, regardless of the lesion being synchronous or metachronous. The biological behavior of metastatic RCC is unpredictable and only early diagnosis and treatment may favorably affect patient survival. Thus, metastatic RCC should be included in the differential diagnosis of all enlarging cutaneous nodules, wherever they develop.

Original languageEnglish
Pages (from-to)401-404
Number of pages4
JournalInternational Journal of Urology
Issue number4
Publication statusPublished - Apr 2005


  • Acrometastasis
  • Renal cell carcinoma
  • Synchronous metastasis

ASJC Scopus subject areas

  • Urology


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