Renal denervation for treatment of uncontrolled hypertension in an Asian population: results from the Global SYMPLICITY Registry in South Korea (GSR Korea)

B. K. Kim, M. Böhm, F. Mahfoud, G. Mancia, S. Park, M. K. Hong, H. S. Kim, S. J. Park, C. G. Park, K. B. Seung, H. C. Gwon, D. J. Choi, T. H. Ahn, C. J. Kim, H. M. Kwon, M. Esler, Y. S. Jang

Research output: Contribution to journalArticlepeer-review

Abstract

Reports detailing the response of hypertensive patients to renal denervation (RDN) in Asian patients are limited. We evaluated 6- and 12-month outcomes after RDN in an Asian population and compared outcomes to a primarily Caucasian population. The Global SYMPLICITY Registry (GSR) is a prospective, all-comer, worldwide registry that evaluates the safety and effectiveness of RDN and includes the Korean registry substudy (GSR Korea) and a Caucasian subset (GSR Caucasian). Given differences in baseline characteristics among GSR Korea (n=93) as compared with GSR Caucasian (n=169) patients, including lower baseline office systolic blood pressure (SBP), lower body mass index and differences in medications, propensity score adjustment was performed when comparing the change in SBP between subsets. The 6- and 12-month change in SBP in GSR Korea was −19.4±17.2 and −27.2±18.1 mm Hg, respectively (P

Original languageEnglish
JournalJournal of Human Hypertension
DOIs
Publication statusAccepted/In press - Jul 9 2015

ASJC Scopus subject areas

  • Internal Medicine

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