Renal leiomyosarcoma: A report of two cases

Gabriele Gaggero, Bruno Spina, Francesca Sarocchi, Gian Luigi Ravetti, Carlo Toncini, Giulio Fraternali Orcioni, Carlo Greco, António Lopez-Beltran

Research output: Contribution to journalArticlepeer-review


BACKGROUND: Leiomyosarcoma represents a rather uncommon malignancy, and reports of cases characterized by a renal genesis are particularly rare. CASES: We describe 2 cases of leiomyosarcoma of the kidney, in a 63-year-old woman and in a 53-year-old man, respectively. Both tumors share a common immunohistochemical profile with a strong positivity for smooth muscle actin, a focal positivity for desmin, and negativity for cytokeratins and other markers. CONCLUSION: We provide a comparison between our findings and the data available in the literature, and we note an interesting relatively long survival in our patients (10 months for the first case and 20 months for the second case).

Original languageEnglish
Pages (from-to)369-374
Number of pages6
JournalAnalytical and Quantitative Cytology and Histology
Issue number6
Publication statusPublished - 2015


  • Carcinoma, renal cell
  • Follow-up studies
  • Kidney
  • Kidney neoplasms
  • Leiomyosarcoma
  • Medicine in literature
  • Nephrectomy
  • Renal cancer
  • Renal neoplasms

ASJC Scopus subject areas

  • Anatomy
  • Histology
  • Medicine(all)


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