Renal leiomyosarcoma: A report of two cases

Gabriele Gaggero; Bruno Spina; Francesca Sarocchi; Gian Luigi Ravetti; Carlo Toncini; Giulio Fraternali Orcioni; Carlo Greco; António Lopez-Beltran

Renal leiomyosarcoma: A report of two cases

Gabriele Gaggero, Bruno Spina, Francesca Sarocchi, Gian Luigi Ravetti, Carlo Toncini, Giulio Fraternali Orcioni, Carlo Greco, António Lopez-Beltran

A.O.U. San Martino - IST, Istituto Nazionale Ricerca sul Cancro (GENOVA)

Research output: Contribution to journal › Article › peer-review

Abstract

BACKGROUND: Leiomyosarcoma represents a rather uncommon malignancy, and reports of cases characterized by a renal genesis are particularly rare. CASES: We describe 2 cases of leiomyosarcoma of the kidney, in a 63-year-old woman and in a 53-year-old man, respectively. Both tumors share a common immunohistochemical profile with a strong positivity for smooth muscle actin, a focal positivity for desmin, and negativity for cytokeratins and other markers. CONCLUSION: We provide a comparison between our findings and the data available in the literature, and we note an interesting relatively long survival in our patients (10 months for the first case and 20 months for the second case).

Original language	English
Pages (from-to)	369-374
Number of pages	6
Journal	Analytical and Quantitative Cytology and Histology
Volume	37
Issue number	6
Publication status	Published - 2015

Keywords

Carcinoma, renal cell
Follow-up studies
Kidney
Kidney neoplasms
Leiomyosarcoma
Medicine in literature
Nephrectomy
Renal cancer
Renal neoplasms

ASJC Scopus subject areas

Anatomy
Histology
Medicine(all)

Cite this

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title = "Renal leiomyosarcoma: A report of two cases",

abstract = "BACKGROUND: Leiomyosarcoma represents a rather uncommon malignancy, and reports of cases characterized by a renal genesis are particularly rare. CASES: We describe 2 cases of leiomyosarcoma of the kidney, in a 63-year-old woman and in a 53-year-old man, respectively. Both tumors share a common immunohistochemical profile with a strong positivity for smooth muscle actin, a focal positivity for desmin, and negativity for cytokeratins and other markers. CONCLUSION: We provide a comparison between our findings and the data available in the literature, and we note an interesting relatively long survival in our patients (10 months for the first case and 20 months for the second case).",

keywords = "Carcinoma, renal cell, Follow-up studies, Kidney, Kidney neoplasms, Leiomyosarcoma, Medicine in literature, Nephrectomy, Renal cancer, Renal neoplasms",

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T1 - Renal leiomyosarcoma

T2 - A report of two cases

AU - Gaggero, Gabriele

AU - Spina, Bruno

AU - Sarocchi, Francesca

AU - Ravetti, Gian Luigi

AU - Toncini, Carlo

AU - Orcioni, Giulio Fraternali

AU - Greco, Carlo

AU - Lopez-Beltran, António

PY - 2015

Y1 - 2015

N2 - BACKGROUND: Leiomyosarcoma represents a rather uncommon malignancy, and reports of cases characterized by a renal genesis are particularly rare. CASES: We describe 2 cases of leiomyosarcoma of the kidney, in a 63-year-old woman and in a 53-year-old man, respectively. Both tumors share a common immunohistochemical profile with a strong positivity for smooth muscle actin, a focal positivity for desmin, and negativity for cytokeratins and other markers. CONCLUSION: We provide a comparison between our findings and the data available in the literature, and we note an interesting relatively long survival in our patients (10 months for the first case and 20 months for the second case).

AB - BACKGROUND: Leiomyosarcoma represents a rather uncommon malignancy, and reports of cases characterized by a renal genesis are particularly rare. CASES: We describe 2 cases of leiomyosarcoma of the kidney, in a 63-year-old woman and in a 53-year-old man, respectively. Both tumors share a common immunohistochemical profile with a strong positivity for smooth muscle actin, a focal positivity for desmin, and negativity for cytokeratins and other markers. CONCLUSION: We provide a comparison between our findings and the data available in the literature, and we note an interesting relatively long survival in our patients (10 months for the first case and 20 months for the second case).

KW - Carcinoma, renal cell

KW - Follow-up studies

KW - Kidney

KW - Kidney neoplasms

KW - Leiomyosarcoma

KW - Medicine in literature

KW - Nephrectomy

KW - Renal cancer

KW - Renal neoplasms

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Renal leiomyosarcoma: A report of two cases

Abstract

Keywords

ASJC Scopus subject areas

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