Renal manifestations of metabolic disorders in children

Francesco Emma, William G. vant Hoff, Carlo Dionisi Vici

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

While the majority of children with renal dysfunction have a structural, immunological, or infective disorder, some have a metabolic defect arising from an abnormality in the biochemical pathways of cell metabolism. Moreover, improved survival of patients with metabolic disorders has uncovered in many cases symptoms secondary to chronic renal lesions that were not apparent when these diseases where first described (e.g., methylmalonic acidemia). Conversely, extrarenal manifestations have become apparent in other patients with metabolic diseases that during childhood manifest primarily with isolated renal or urological symptoms (e.g., nephropathic cystinosis). Pediatric nephrologists should always remain vigilant to the possibility of a metabolic disorder, especially when children have extrarenal symptoms.

Original languageEnglish
Title of host publicationPediatric Nephrology, Seventh Edition
PublisherSpringer Berlin Heidelberg
Pages1569-1607
Number of pages39
ISBN (Print)9783662435960, 9783662435953
DOIs
Publication statusPublished - Jan 1 2015

Fingerprint

Kidney
Cystinosis
Metabolic Diseases
Pediatrics
Survival
Nephrologists
Methylmalonic acidemia

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Emma, F., vant Hoff, W. G., & Vici, C. D. (2015). Renal manifestations of metabolic disorders in children. In Pediatric Nephrology, Seventh Edition (pp. 1569-1607). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-662-43596-0_46

Renal manifestations of metabolic disorders in children. / Emma, Francesco; vant Hoff, William G.; Vici, Carlo Dionisi.

Pediatric Nephrology, Seventh Edition. Springer Berlin Heidelberg, 2015. p. 1569-1607.

Research output: Chapter in Book/Report/Conference proceedingChapter

Emma, F, vant Hoff, WG & Vici, CD 2015, Renal manifestations of metabolic disorders in children. in Pediatric Nephrology, Seventh Edition. Springer Berlin Heidelberg, pp. 1569-1607. https://doi.org/10.1007/978-3-662-43596-0_46
Emma F, vant Hoff WG, Vici CD. Renal manifestations of metabolic disorders in children. In Pediatric Nephrology, Seventh Edition. Springer Berlin Heidelberg. 2015. p. 1569-1607 https://doi.org/10.1007/978-3-662-43596-0_46
Emma, Francesco ; vant Hoff, William G. ; Vici, Carlo Dionisi. / Renal manifestations of metabolic disorders in children. Pediatric Nephrology, Seventh Edition. Springer Berlin Heidelberg, 2015. pp. 1569-1607
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