Renal Resistive Index of the Main Renal Arteries and Transmitral Flow in Hypertensive Patients

Michele Antonio Prencipe, Andrea Fontana, Chiara Di Giorgio, Angela Maria Pellegrino, Antonio Mangiacotti, Massimiliano Copetti, Filippo Aucella

Research output: Contribution to journalArticlepeer-review


In hypertensive patients, diastolic dysfunction is related to increased resistive index (RI) of parenchymal renal arteries. To determine the existence of a link between RI of the main renal arteries (RRI) and diastolic dysfunction, a group of 127 hypertensive patients, with glomerular filtration rates >50 mL/min (mean estimated glomerular filtration rate: 88.6 ± 15.2 mL/min) and no comorbidities, was studied. RRI and transmitral flow were evaluated using the deceleration time (DT) and E/A ratio. A statistically significant correlation between RRI and DT (>240 ms) was noted (p < 0.001). The RRI cutoff that best discriminated patients with DT >240 ms was 0.675. For each unitary increment of 10 mm in DT, the log-transformed RRI significantly increased by a mean of 0.006 point (p < 0.001). This study revealed the importance of the link between RRI and transmitral DT in addition to the renowned significance of the increase in RI as a cardiovascular risk factor in hypertensive patients without comorbidities.

Original languageEnglish
Pages (from-to)2700-2710
Number of pages11
JournalUltrasound in Medicine and Biology
Issue number10
Publication statusPublished - Oct 2020


  • Diastolic dysfunction
  • Hypertension
  • Renal arteries
  • Resistive index
  • Transmitral flow

ASJC Scopus subject areas

  • Biophysics
  • Radiological and Ultrasound Technology
  • Acoustics and Ultrasonics


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