TY - JOUR
T1 - Renal Resistive Index of the Main Renal Arteries and Transmitral Flow in Hypertensive Patients
AU - Prencipe, Michele Antonio
AU - Fontana, Andrea
AU - Di Giorgio, Chiara
AU - Pellegrino, Angela Maria
AU - Mangiacotti, Antonio
AU - Copetti, Massimiliano
AU - Aucella, Filippo
PY - 2020/10
Y1 - 2020/10
N2 - In hypertensive patients, diastolic dysfunction is related to increased resistive index (RI) of parenchymal renal arteries. To determine the existence of a link between RI of the main renal arteries (RRI) and diastolic dysfunction, a group of 127 hypertensive patients, with glomerular filtration rates >50 mL/min (mean estimated glomerular filtration rate: 88.6 ± 15.2 mL/min) and no comorbidities, was studied. RRI and transmitral flow were evaluated using the deceleration time (DT) and E/A ratio. A statistically significant correlation between RRI and DT (>240 ms) was noted (p < 0.001). The RRI cutoff that best discriminated patients with DT >240 ms was 0.675. For each unitary increment of 10 mm in DT, the log-transformed RRI significantly increased by a mean of 0.006 point (p < 0.001). This study revealed the importance of the link between RRI and transmitral DT in addition to the renowned significance of the increase in RI as a cardiovascular risk factor in hypertensive patients without comorbidities.
AB - In hypertensive patients, diastolic dysfunction is related to increased resistive index (RI) of parenchymal renal arteries. To determine the existence of a link between RI of the main renal arteries (RRI) and diastolic dysfunction, a group of 127 hypertensive patients, with glomerular filtration rates >50 mL/min (mean estimated glomerular filtration rate: 88.6 ± 15.2 mL/min) and no comorbidities, was studied. RRI and transmitral flow were evaluated using the deceleration time (DT) and E/A ratio. A statistically significant correlation between RRI and DT (>240 ms) was noted (p < 0.001). The RRI cutoff that best discriminated patients with DT >240 ms was 0.675. For each unitary increment of 10 mm in DT, the log-transformed RRI significantly increased by a mean of 0.006 point (p < 0.001). This study revealed the importance of the link between RRI and transmitral DT in addition to the renowned significance of the increase in RI as a cardiovascular risk factor in hypertensive patients without comorbidities.
KW - Diastolic dysfunction
KW - Hypertension
KW - Renal arteries
KW - Resistive index
KW - Transmitral flow
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U2 - 10.1016/j.ultrasmedbio.2020.06.017
DO - 10.1016/j.ultrasmedbio.2020.06.017
M3 - Article
C2 - 32703658
AN - SCOPUS:85088112922
VL - 46
SP - 2700
EP - 2710
JO - Ultrasound in Medicine and Biology
JF - Ultrasound in Medicine and Biology
SN - 0301-5629
IS - 10
ER -