Renal transplantation in patients with IgA mesangial glomerulonephritis

Claudio Ponticelli, Lara Traversi, Giovanni Banfi

Research output: Contribution to journalArticle

Abstract

Most patients with IgA nephritis are suitable candidates for renal transplantation. In about 33% of patients the disease may recur after transplantation, although there are differences in the various series because of the different criteria for biopsy, the different length of follow-up and the different ethnicities. Living donation, genetic factors and time of progression of original disease have been found to be related with the risk of recurrence by some investigators, but these associations were not confirmed by other studies. The graft survival in patients with IgA nephritis is similar or even better than that observed with other renal diseases. The available data indicate that recurrence has a little impact on the 10-yr graft survival. However, a minority of patients may show a rapid progressive course after recurrence. Little information is available on the impact of recurrence in the very long term. There is no established treatment for preventing or treating the recurrence of IgA nephritis.

Original languageEnglish
Pages (from-to)334-338
Number of pages5
JournalPediatric Transplantation
Volume8
Issue number4
DOIs
Publication statusPublished - Aug 2004

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Keywords

  • IgA nephritis
  • Recurrent glomerulonephritis
  • Renal transplantation

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Transplantation

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