Il trapianto renale nel Nord Italia Transplant program (NITp): assegnazione degli organi e risultati.

Translated title of the contribution: Renal transplantation in the North Italy Transplant program (NITp): Organ allocation and results

M. Cardillo, F. Barraco, N. De Fazio, G. Rossini, C. Pizzi, L. Boschiero, A. Nocera, P. Rigotti, F. Marchini, S. Sandrini, G. Frova, S. Chiaramonte, C. Maresca, R. Caldara, P. Messa, L. Berardinelli, A. Ambrosini, D. Montanaro, T. Rampino, E. MinettiE. Gotti, M. Scalamogna

Research output: Contribution to journalArticle

Abstract

Renal transplantation is an effective therapeutic tool for patients with end-stage renal diseases (ESRDs). Data reported in this article summarize the results obtained from 30 years' activity in the North Italy Transplant program (NITp), the first transplant organization in Italy that implemented a donor procurement and organ transplantation network. In the NITp kidney allocation is governed by a computerized algorithm, NITK3, put in place in 1997, aimed at ensuring equity, transparency and traceability during the stages of the allocation decision-making process. The NITp working group has recognized the NITK3 criteria and they are periodically reviewed following the results of the analysis of patients' transplantation odds. The results obtained with the use of the NITK3 algorithm have been very satisfactory: after 6 yrs, a significantly higher percentage of patients at immunological risk (sensitized or waiting for re-transplant), of patients waiting for >3 yrs and of patients with 0-1 HLA A,B,DR mismatches have been transplanted. Moreover, a higher percentage of kidneys were used locally (in a hospital within the procurement area), and this is known to stimulate donor procurement. Finally, we performed a preliminary statistical analysis of transplants carried out from 1998-2002 in 5/16 centers of the NITp area, demonstrating the quality of the NITp program in terms of patient and graft survival, and that donor and recipient age are the variables significantly impacting on transplant results.

Original languageItalian
JournalGiornale italiano di nefrologia : organo ufficiale della Società italiana di nefrologia
Volume22 Suppl 31
Publication statusPublished - Jan 2005

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Kidney Transplantation
Italy
Transplants
Tissue Donors
Kidney
HLA-A Antigens
HLA-B Antigens
Organ Transplantation
Graft Survival
Chronic Kidney Failure
Decision Making
Transplantation

ASJC Scopus subject areas

  • Nephrology

Cite this

Il trapianto renale nel Nord Italia Transplant program (NITp) : assegnazione degli organi e risultati. / Cardillo, M.; Barraco, F.; De Fazio, N.; Rossini, G.; Pizzi, C.; Boschiero, L.; Nocera, A.; Rigotti, P.; Marchini, F.; Sandrini, S.; Frova, G.; Chiaramonte, S.; Maresca, C.; Caldara, R.; Messa, P.; Berardinelli, L.; Ambrosini, A.; Montanaro, D.; Rampino, T.; Minetti, E.; Gotti, E.; Scalamogna, M.

In: Giornale italiano di nefrologia : organo ufficiale della Società italiana di nefrologia, Vol. 22 Suppl 31, 01.2005.

Research output: Contribution to journalArticle

Cardillo, M, Barraco, F, De Fazio, N, Rossini, G, Pizzi, C, Boschiero, L, Nocera, A, Rigotti, P, Marchini, F, Sandrini, S, Frova, G, Chiaramonte, S, Maresca, C, Caldara, R, Messa, P, Berardinelli, L, Ambrosini, A, Montanaro, D, Rampino, T, Minetti, E, Gotti, E & Scalamogna, M 2005, 'Il trapianto renale nel Nord Italia Transplant program (NITp): assegnazione degli organi e risultati.', Giornale italiano di nefrologia : organo ufficiale della Società italiana di nefrologia, vol. 22 Suppl 31.
Cardillo, M. ; Barraco, F. ; De Fazio, N. ; Rossini, G. ; Pizzi, C. ; Boschiero, L. ; Nocera, A. ; Rigotti, P. ; Marchini, F. ; Sandrini, S. ; Frova, G. ; Chiaramonte, S. ; Maresca, C. ; Caldara, R. ; Messa, P. ; Berardinelli, L. ; Ambrosini, A. ; Montanaro, D. ; Rampino, T. ; Minetti, E. ; Gotti, E. ; Scalamogna, M. / Il trapianto renale nel Nord Italia Transplant program (NITp) : assegnazione degli organi e risultati. In: Giornale italiano di nefrologia : organo ufficiale della Società italiana di nefrologia. 2005 ; Vol. 22 Suppl 31.
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AU - Barraco, F.

AU - De Fazio, N.

AU - Rossini, G.

AU - Pizzi, C.

AU - Boschiero, L.

AU - Nocera, A.

AU - Rigotti, P.

AU - Marchini, F.

AU - Sandrini, S.

AU - Frova, G.

AU - Chiaramonte, S.

AU - Maresca, C.

AU - Caldara, R.

AU - Messa, P.

AU - Berardinelli, L.

AU - Ambrosini, A.

AU - Montanaro, D.

AU - Rampino, T.

AU - Minetti, E.

AU - Gotti, E.

AU - Scalamogna, M.

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