Reoperation after failure of antireflux repairs

A. Peracchia, L. Bonavina

Research output: Contribution to journalArticlepeer-review


Seventy consecutive patients presenting with symptoms after one or more antireflux repairs for gastroesophageal reflux disease underwent reoperation. Five patients had been operated on laparoscopically. The indications for reoperation were based on severity of symptoms and results of objective investigation. Surgical therapy was tailored to the individual patient based on pathophysiological abnormalities and the results of intraoperative assessment. Reflux symptoms and dysphagia represented the major complaint in 62.8% and 35.7% of patients, respectively. The most common pathophysiological abnormality was an incompetent lower esophageal sphincter. Intraoperative assessment showed a disrupted or misplaced repair in 77% of the patients. The most commonly performed reoperation was a partial or total fundoplication (54.3%), followed by antrectomy and Roux-en-Y anastomosis (25.7%). There was no mortality. Postoperative morbidity rate was 8.5%. At a median follow-up of 48 months, 87% of patients were scored as Visick 1-2 and 90% declared themselves satisfied with the results of reoperation. Failure of antireflux surgery may be due to errors in patient selection, errors in the choice of the operation, or technical errors in the performance of the operation. Management of such patients requires expertise in physiological assessment and in surgical technique. For a successful outcome, the surgical approach should be tailored to residual anatomy and function of the foregut.

Original languageEnglish
Pages (from-to)81-84
Number of pages4
JournalGastroenterology International
Issue numberSUPPL. 2
Publication statusPublished - 1997


  • Laparoscopic surgery
  • Lower esophageal sphincter
  • Nissen fundoplication

ASJC Scopus subject areas

  • Gastroenterology


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