Ripetibilita e validazione di un nuovo sistema telemetrico portatile di calorimetria indiretta

Translated title of the contribution: Repeatability and validation of a new portable telemetric indirect calorimetry system

F. W. Guglielmi, T. Mastronuzzi, A. Panarese, C. Panella, A. Francavilla

Research output: Contribution to journalArticlepeer-review


Aim of the study: Recently a new indirect calorimetry system has been proposed (K4) suitable for measurement of gaseous exchanges during exercise due to the miniaturized structure and the telemetric transmission. The purpose of this study was to test the reliability and validity of the telemetric system for measuring oxygen uptake (VO2), carbon dioxide output (VCO2) and resting energy expenditure (REE). Patients and methods: Twelve subjects (10 M, 2 F), 2 controls and 10 patients with different types of diseases (chronic hepatitis 3, liver cirrhosis 3, cirrhosis with hepatocellular carcinoma 1, chronic pancreatitis 3) were enrolled and studied, after 12 hours' fasting, during two consecutive days. Tests were started after 30-40 minutes' resting. The reliability was measured in 5 patients in 3 successive days. As regards the validity, K4 measurements were compared with those obtained with the Horizon MMC, Sensormedics system. Results: A low coefficient of variation was calculated for each parameter (VO2 = 3.6 ± 0.9; VCO2 = 4.6 ± 1.1; VE = 3.3 ± 0.7; BEE = 2.2 ± 0.5). The telemetric system showed a significant (p <0.02) overestimation of VCO2 measurements (K4 2.8 ± 0.3 mL/min/kg; MMC 2.4 ± 0.2 ml/min/kg) while VO2 (K4 3.1 ± 0.3 mL/min/kg; MMC 3.0 ± 0.3 mL/min/kg) and REE (K4 1521 ± 367 kcal/day; MMC 1360 ± 172 kcal/day) measures did not differ significantly between techniques. These data were confirmed by limits of agreement that were small enough to be acceptable for physiological parameters (VO2 -0.4 + 0.6 mL/min/kg; VCO2 -1.1 +0.5 mL/min/kg; REE -4.9 + 3.1 kcal/min/kg). Conclusion: We conclude that the telemetric system represents an adequate alternative to the Horizon MMC, Sensormedics system both for VO2 and REE measurement only if the rests are performed after 30-40 minutes' resting. Our data confirm the suitability of the K4 system for metabolic studies and underlines its aptitude for clinical studies aimed at estimating the metabolic changes induced in skeletal muscle by exercise.

Translated title of the contributionRepeatability and validation of a new portable telemetric indirect calorimetry system
Original languageItalian
Pages (from-to)126-129
Number of pages4
JournalRivista Italiana di Nutrizione Parenterale ed Enterale
Issue number3
Publication statusPublished - 1999

ASJC Scopus subject areas

  • Food Science
  • Anatomy
  • Critical Care and Intensive Care Medicine
  • Nutrition and Dietetics


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