Repeated vaccinations do not improve specific immune defenses against Hepatitis B in non-responder health care workers

Salvatore Zaffina, Valentina Marcellini, Anna Paola Santoro, Marco Scarsella, Vincenzo Camisa, Maria Rosaria Vinci, Anna Maria Musolino, Luciana Nicolosi, M. Manuela Rosado, Rita Carsetti

Research output: Contribution to journalArticlepeer-review

Abstract

Hepatitis B is a major infectious occupational hazard for health care workers and can be prevented with a safe and effective vaccine. The serum titer of anti-HBsAg antibodies is the most commonly used correlate of protection and post-vaccination anti-HBsAg concentrations of ≥10. mIU/ml are considered protective. Subjects with post-vaccination anti-HBsAg titers of

Original languageEnglish
Pages (from-to)6902-6910
Number of pages9
JournalVaccine
Volume32
Issue number51
DOIs
Publication statusPublished - 2014

Keywords

  • Anti-HBsAg specific antibodies
  • Hepatitis B vaccine
  • Memory B cells
  • Non-responders

ASJC Scopus subject areas

  • Immunology and Microbiology(all)
  • Infectious Diseases
  • Public Health, Environmental and Occupational Health
  • veterinary(all)
  • Molecular Medicine
  • Medicine(all)

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