Repeated vaccinations do not improve specific immune defenses against Hepatitis B in non-responder health care workers

Salvatore Zaffina, Valentina Marcellini, Anna Paola Santoro, Marco Scarsella, Vincenzo Camisa, Maria Rosaria Vinci, Anna Maria Musolino, Luciana Nicolosi, M. Manuela Rosado, Rita Carsetti

Research output: Contribution to journalArticle

Abstract

Hepatitis B is a major infectious occupational hazard for health care workers and can be prevented with a safe and effective vaccine. The serum titer of anti-HBsAg antibodies is the most commonly used correlate of protection and post-vaccination anti-HBsAg concentrations of ≥10. mIU/ml are considered protective. Subjects with post-vaccination anti-HBsAg titers of

Original languageEnglish
Pages (from-to)6902-6910
Number of pages9
JournalVaccine
Volume32
Issue number51
DOIs
Publication statusPublished - 2014

Fingerprint

hepatitis B
health care workers
Hepatitis B Surface Antigens
Hepatitis B
Vaccination
vaccination
Delivery of Health Care
health hazards
Occupational Health
vaccines
antibodies
Anti-Idiotypic Antibodies
Vaccines
Serum

Keywords

  • Anti-HBsAg specific antibodies
  • Hepatitis B vaccine
  • Memory B cells
  • Non-responders

ASJC Scopus subject areas

  • Immunology and Microbiology(all)
  • Infectious Diseases
  • Public Health, Environmental and Occupational Health
  • veterinary(all)
  • Molecular Medicine
  • Medicine(all)

Cite this

Repeated vaccinations do not improve specific immune defenses against Hepatitis B in non-responder health care workers. / Zaffina, Salvatore; Marcellini, Valentina; Santoro, Anna Paola; Scarsella, Marco; Camisa, Vincenzo; Vinci, Maria Rosaria; Musolino, Anna Maria; Nicolosi, Luciana; Rosado, M. Manuela; Carsetti, Rita.

In: Vaccine, Vol. 32, No. 51, 2014, p. 6902-6910.

Research output: Contribution to journalArticle

Zaffina, Salvatore ; Marcellini, Valentina ; Santoro, Anna Paola ; Scarsella, Marco ; Camisa, Vincenzo ; Vinci, Maria Rosaria ; Musolino, Anna Maria ; Nicolosi, Luciana ; Rosado, M. Manuela ; Carsetti, Rita. / Repeated vaccinations do not improve specific immune defenses against Hepatitis B in non-responder health care workers. In: Vaccine. 2014 ; Vol. 32, No. 51. pp. 6902-6910.
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