TY - CHAP
T1 - Report on liver cell transplantation using human fetal liver cells
AU - Pietrosi, Giada
AU - Chinnici, Cinzia
PY - 2017
Y1 - 2017
N2 - In an era of organ shortage, human fetuses donated after medically indicated abortion could be considered a potential liver donor for hepatic cell isolation. We investigated transplantation of fetal liver cells as a strategy to support liver functionality in end-stage liver disease. Here, we report our protocol of human fetal liver cells (hFLC) isolation in fetuses from 17 to 22 gestational weeks, and our clinical procedure of hFLC transplantation through the splenic artery.
AB - In an era of organ shortage, human fetuses donated after medically indicated abortion could be considered a potential liver donor for hepatic cell isolation. We investigated transplantation of fetal liver cells as a strategy to support liver functionality in end-stage liver disease. Here, we report our protocol of human fetal liver cells (hFLC) isolation in fetuses from 17 to 22 gestational weeks, and our clinical procedure of hFLC transplantation through the splenic artery.
KW - Chronic liver disease
KW - Collagenase perfusion
KW - Fetal liver
KW - Fetal stem cell transplantation
KW - Liver cell transplantation
KW - Liver progenitors
KW - Liver stem cell isolation
UR - http://www.scopus.com/inward/record.url?scp=84995483264&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84995483264&partnerID=8YFLogxK
U2 - 10.1007/978-1-4939-6506-9_20
DO - 10.1007/978-1-4939-6506-9_20
M3 - Chapter
AN - SCOPUS:84995483264
VL - 1506
T3 - Methods in Molecular Biology
SP - 283
EP - 294
BT - Methods in Molecular Biology
PB - Humana Press Inc.
ER -