Representation of different trigeminal divisions within the primary and secondary human somatosensory cortex

G. D. Iannetti, C. A. Porro, P. Pantano, P. L. Romanelli, F. Galeotti, G. Cruccu

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Clinical, neurophysiological, and neuroimaging studies have yielded controversial results about the representation of the face in the somatosensory cortex. To clarify this issue we mechanically stimulated the left forehead (ophthalmic trigeminal division, V1) and left lower lip (mandibular trigeminal division, V3) in 14 healthy volunteers during acquisition of whole-brain fMRI images. During V1 and V3 stimulation the fMRI signal in the primary (SI) and secondary (SII) somatosensory cortices in the contralateral hemisphere increased. Within both SI and SII, the foci activated by stimulation of the two trigeminal divisions largely overlapped. In contrast, the ipsilateral representation differed. Whereas V3 stimulation activated the contralateral somatosensory cortex alone, V1 stimulation activated SI and SII bilaterally. These results to some extent contrast with electrophysiological data in monkeys and disclose distinct cortical representations within facial territories in humans.

Original languageEnglish
Pages (from-to)906-912
Number of pages7
JournalNeuroImage
Volume19
Issue number3
DOIs
Publication statusPublished - Jul 1 2003

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Somatosensory Cortex
Magnetic Resonance Imaging
Forehead
Lip
Neuroimaging
Haplorhini
Healthy Volunteers
Brain

Keywords

  • fMRI
  • Ipsilateral representation
  • Primary somatosensory cortex
  • Secondary somatosensory cortex
  • Trigeminal system

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Neurology

Cite this

Representation of different trigeminal divisions within the primary and secondary human somatosensory cortex. / Iannetti, G. D.; Porro, C. A.; Pantano, P.; Romanelli, P. L.; Galeotti, F.; Cruccu, G.

In: NeuroImage, Vol. 19, No. 3, 01.07.2003, p. 906-912.

Research output: Contribution to journalArticle

Iannetti, G. D. ; Porro, C. A. ; Pantano, P. ; Romanelli, P. L. ; Galeotti, F. ; Cruccu, G. / Representation of different trigeminal divisions within the primary and secondary human somatosensory cortex. In: NeuroImage. 2003 ; Vol. 19, No. 3. pp. 906-912.
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