Reproducibility of heart rate turbulence indexes in heart failure patients

Gianni D'Addio, Mario Cesarelli, Graziamaria Corbi, Maria Romano, Giuseppe Furgi, Nicola Ferrara, Franco Rengo

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Cardiovascular oscillations following spontaneous ventricular premature complexes (VPC) are characterized by a short-term heart rate fluctuation known as heart rate turbulence (HRT) described by the so-called turbulence onset (TO) and slope (TS). Despite a recent written consensus on the standard of HRT measurement, reproducibility data are lacking. Aim of the paper was a reproducibility study of HRT indexes in heart failure patients (HF). Eleven HF patients underwent two 24h ECG Holter recordings, spaced 7±5 days. A paired t test was used to assess the clinical stability of patients during the study period and the number of PVC in Holter recordings' couples. Both TO and TS indexes were calculated for each isolated VPC, and due to their skewed distribution, reproducibility of median and mean TO and TS was studied by Bland-Altman technique. Results showed that median HRT indexes might be preferred to commonly suggested mean values and that, although TO showed lower bias value than TS, TS can be considered much more reproducible than TO, comparing limits of agreements with normal values. This preliminary results suggest the use of medians instead of mean HRT indexes values and a reliability of the turbulence slope greater than the turbulence onset index.

Original languageEnglish
Title of host publication2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
Pages2573-2576
Number of pages4
DOIs
Publication statusPublished - 2010
Event2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 - Buenos Aires, Argentina
Duration: Aug 31 2010Sep 4 2010

Other

Other2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
CountryArgentina
CityBuenos Aires
Period8/31/109/4/10

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ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

D'Addio, G., Cesarelli, M., Corbi, G., Romano, M., Furgi, G., Ferrara, N., & Rengo, F. (2010). Reproducibility of heart rate turbulence indexes in heart failure patients. In 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 (pp. 2573-2576). [5626653] https://doi.org/10.1109/IEMBS.2010.5626653