Reproducibility of real-time shear wave elastography in the evaluation of liver elasticity

Giovanna Ferraioli, Carmine Tinelli, Mabel Zicchetti, Elisabetta Above, Gianluigi Poma, Marta Di Gregorio, Carlo Filice

Research output: Contribution to journalArticle

Abstract

Objective: To evaluate the reproducibility of real-time shear wave elastography in assessing liver elasticity in healthy volunteers. Methods: Forty-two volunteers were studied in day 1. Shear wave elastography studies were performed by using the ultrasound system Aixplorer™ (SuperSonic Imagine S.A., Aix-en-Provence, France) with a convex broadband probe. Measurements were carried by two operators, an expert (operator 1) and a novice (operator 2). Examinations were performed on the right lobe of the liver. Each operator performed 10 consecutive measurements in each volunteer. In a subset of volunteers (n = 18) measurements were performed twice on two different days (day 1 and day 2). Intraobserver and interobserver agreement were assessed by intraclass correlation coefficient. Results: Intraobserver agreement between measurements performed in the same subject in the same day (day 1 or day 2) showed intraclass correlation coefficient values of 0.95 (95% confidence interval, 0.93-0.98) and 0.93 (95% confidence interval, 0.90-0.96) for operator 1 and operator 2, respectively. Intraobserver agreement between measurements performed in the same subject in different days showed intraclass correlation coefficient values of 0.84 (95% confidence interval, 0.69-0.98) and 0.65 (95% confidence interval, 0.39-0.91) for operator 1 and operator 2, respectively. Interobserver agreement was 0.88 (95% confidence interval, 0.82-0.94). Conclusions: The results of this study show that shear wave elastography is a reliable and reproducible noninvasive method for the assessment of liver elasticity. Expert operator had higher reproducibility of measurements over time than novice operator.

Original languageEnglish
Pages (from-to)3102-3106
Number of pages5
JournalEuropean Journal of Radiology
Volume81
Issue number11
DOIs
Publication statusPublished - Nov 2012

Keywords

  • Elastography
  • Intraclass correlation coefficient
  • Liver
  • Reproducibility studies
  • Ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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