TY - JOUR
T1 - Reproductive, menstrual, and other hormone-related factors and risk of renal cell cancer
AU - Zucchetto, Antonella
AU - Talamini, Renato
AU - Dal Maso, Luigino
AU - Negri, Eva
AU - Polesel, Jerry
AU - Ramazzotti, Valerio
AU - Montella, Maurizio
AU - Canzonieri, Vincenzo
AU - Serraino, Diego
AU - La Vecchia, Carlo
AU - Franceschi, Silvia
PY - 2008/11/1
Y1 - 2008/11/1
N2 - A role of hormone-related factors in renal cell cancer (RCC) etiology has been hypothesized, but the epidemiological evidence is inconsistent. The present study aimed at evaluating the effect of reproductive, menstrual and other gender-specific variables on RCC risk among women. This study is part of a larger hospital-based, case-control study on RCC risk, conducted in northern, central and southern Italy. Cases were 273 women, below age 80, with histologically confirmed, incident RCC. Controls were 546 women hospitalized for acute, nonneoplastic conditions, frequency-matched to cases by age and center. Odds ratios (OR) and 95% confidence intervals (CI) were computed using multiple logistic regression models. RCC risk was inversely related to age at first birth (OR = 0.7, 95% CI 0.5-1.0, for ≥25 years vs.
AB - A role of hormone-related factors in renal cell cancer (RCC) etiology has been hypothesized, but the epidemiological evidence is inconsistent. The present study aimed at evaluating the effect of reproductive, menstrual and other gender-specific variables on RCC risk among women. This study is part of a larger hospital-based, case-control study on RCC risk, conducted in northern, central and southern Italy. Cases were 273 women, below age 80, with histologically confirmed, incident RCC. Controls were 546 women hospitalized for acute, nonneoplastic conditions, frequency-matched to cases by age and center. Odds ratios (OR) and 95% confidence intervals (CI) were computed using multiple logistic regression models. RCC risk was inversely related to age at first birth (OR = 0.7, 95% CI 0.5-1.0, for ≥25 years vs.
KW - Case-control study
KW - Hormones
KW - Hysterectomy
KW - Kidney cancer
KW - Reproductive and menstrual factors
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U2 - 10.1002/ijc.23750
DO - 10.1002/ijc.23750
M3 - Article
C2 - 18711701
AN - SCOPUS:51649101106
VL - 123
SP - 2213
EP - 2216
JO - International Journal of Cancer
JF - International Journal of Cancer
SN - 0020-7136
IS - 9
ER -