Reserpine derivatives with specific hypotensive or sedative activity

S. Garattini, A. Mortari, A. Valsecchi, L. Valzelli

Research output: Contribution to journalArticle

Abstract

RECENTLY it has been reported, by Ciba Laboratories1,2, that two reserpine analogues show more specific effects than reserpine. Methyl-18-O(3-NN-dimethylaminobenzoyl)reserpate (or SU 5171) exhibits sedative activity, while carbethoxysyringoyl-methylreserpate (syrosingopine or SU 3118) is effective in decreasing blood tension (see formulæ).

Original languageEnglish
Pages (from-to)1273-1274
Number of pages2
JournalNature
Volume183
Issue number4670
DOIs
Publication statusPublished - 1959

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