Scarsa influenza dell'ischemia miocardica da sforzo sul rimodellamento ventricolare in pazientiinfartuati con funzione sistolica conseryata

Translated title of the contribution: Residual exertional ischemia does not influence left ventricular remodeling in postinfarction patients with preserved ventricular function

Research output: Contribution to journalArticle

Abstract

BACKGROUND. The effects of acute and recurrent ischemia on ventricular function are well documented. However, the role of residual exertional ischemia in the remodelling process after infarction has not yet been established. In this study, we investigated whether exercise-induced myocardial ischemia influences left ventricular remodelling in patients with recent myocardial infarction and preserved left ventricular function and volumes. METHODS. Sixty-four patients with a first anterior Q wave myocardial infarction were studied at 5 weeks by rest echocardiography and exercise scintigraphy; the echocardiographic examination at rest was repeated 6 months later. Based on the presence and extent of reversible perfusion defects on exercise scintigraphy, patients were classified as having no exertional ischemia (group 1, n = 13 [20%]), mild to moderate ischemia (group 2, n = 32 [50%]) and severe exertional ischemia (group 3, n = 19 [30%]). RESULTS. At 5 weeks after infarction left ventricular volumes, ejection fraction, percent wall motion abnormalities and regional dilatation were similar in the three groups. After 6 months, end-diastolic and end-systolic volumes and regional dilatation did not change in patients in all groups, while ejection fraction and percent wall motion abnormalities showed a slight but significant (p

Translated title of the contributionResidual exertional ischemia does not influence left ventricular remodeling in postinfarction patients with preserved ventricular function
Original languageItalian
Pages (from-to)729-737
Number of pages9
JournalGiornale Italiano di Cardiologia
Volume26
Issue number6
Publication statusPublished - 1996

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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