Resistenza di Pseudomonas aeruginosa a ciprofloxacina e levofloxacina: 1998-2002

Translated title of the contribution: Resistance of Pseudomonas aeruginosa to ciprofloxacin and levofloxacin: 1998-2002

Elena De Vecchi, Lorenzo Drago, Lucia Nicola, Alberto Colombo, Anna Guerra, Loredana Tocalli, Massimo Medaglia, Maria Rita Gismondo

Research output: Contribution to journalArticlepeer-review


The aim of this study was to evaluate resistance rates to ciprofloxacin and levofloxacin of Pseudomonas aeruginosa (n=1917 strains) isolated at Laboratory of Microbiology at L. Sacco Teaching Hospital in Milan, Italy in the period between January 1998 and October 2002. Twenty-five percent of tested strains were isolated from sputum, 18% from bronchial lavage, 10% from urine, 9% from ear, 4.5% from blood and 26% from other materials. Ciprofloxacin-resistant strains were 121/ 411 (29%) in 1998, 158/ 526 (30%) in 1999, 136/ 400 (34%) in 2000, 129/ 390 (33%) in 2001 and 53/ 190 (28%) in 2002. Resistance rates for levofloxacin were 132/472 (28%) in 1999, 104/ 400 (26%) in 2000, 101/ 390 (26 %) in 2001 and 47/ 190 (25%) in 2002. Our data highlight overall stability in resistance to ciprofloxacin and levofloxacin with minor variations for ciprofloxacin. Moreover, in contrast with international worldwide studies, resistance rates to ciprofloxacin remained higher than those related to levofloxacin throughout the period studied.

Translated title of the contributionResistance of Pseudomonas aeruginosa to ciprofloxacin and levofloxacin: 1998-2002
Original languageItalian
Pages (from-to)196-200
Number of pages5
JournalInfezioni in Medicina
Issue number4
Publication statusPublished - 2003

ASJC Scopus subject areas

  • Microbiology (medical)


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