TY - JOUR
T1 - Resistenza di Pseudomonas aeruginosa a ciprofloxacina e levofloxacina
T2 - 1998-2002
AU - De Vecchi, Elena
AU - Drago, Lorenzo
AU - Nicola, Lucia
AU - Colombo, Alberto
AU - Guerra, Anna
AU - Tocalli, Loredana
AU - Medaglia, Massimo
AU - Gismondo, Maria Rita
PY - 2003
Y1 - 2003
N2 - The aim of this study was to evaluate resistance rates to ciprofloxacin and levofloxacin of Pseudomonas aeruginosa (n=1917 strains) isolated at Laboratory of Microbiology at L. Sacco Teaching Hospital in Milan, Italy in the period between January 1998 and October 2002. Twenty-five percent of tested strains were isolated from sputum, 18% from bronchial lavage, 10% from urine, 9% from ear, 4.5% from blood and 26% from other materials. Ciprofloxacin-resistant strains were 121/ 411 (29%) in 1998, 158/ 526 (30%) in 1999, 136/ 400 (34%) in 2000, 129/ 390 (33%) in 2001 and 53/ 190 (28%) in 2002. Resistance rates for levofloxacin were 132/472 (28%) in 1999, 104/ 400 (26%) in 2000, 101/ 390 (26 %) in 2001 and 47/ 190 (25%) in 2002. Our data highlight overall stability in resistance to ciprofloxacin and levofloxacin with minor variations for ciprofloxacin. Moreover, in contrast with international worldwide studies, resistance rates to ciprofloxacin remained higher than those related to levofloxacin throughout the period studied.
AB - The aim of this study was to evaluate resistance rates to ciprofloxacin and levofloxacin of Pseudomonas aeruginosa (n=1917 strains) isolated at Laboratory of Microbiology at L. Sacco Teaching Hospital in Milan, Italy in the period between January 1998 and October 2002. Twenty-five percent of tested strains were isolated from sputum, 18% from bronchial lavage, 10% from urine, 9% from ear, 4.5% from blood and 26% from other materials. Ciprofloxacin-resistant strains were 121/ 411 (29%) in 1998, 158/ 526 (30%) in 1999, 136/ 400 (34%) in 2000, 129/ 390 (33%) in 2001 and 53/ 190 (28%) in 2002. Resistance rates for levofloxacin were 132/472 (28%) in 1999, 104/ 400 (26%) in 2000, 101/ 390 (26 %) in 2001 and 47/ 190 (25%) in 2002. Our data highlight overall stability in resistance to ciprofloxacin and levofloxacin with minor variations for ciprofloxacin. Moreover, in contrast with international worldwide studies, resistance rates to ciprofloxacin remained higher than those related to levofloxacin throughout the period studied.
KW - Bacterial resistance
KW - Ciprofloxacin
KW - Levofloxacin
KW - Pseudomonas aeruginosa
UR - http://www.scopus.com/inward/record.url?scp=0742305755&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0742305755&partnerID=8YFLogxK
M3 - Articolo
C2 - 14988667
AN - SCOPUS:0742305755
VL - 11
SP - 196
EP - 200
JO - Infezioni in Medicina
JF - Infezioni in Medicina
SN - 1124-9390
IS - 4
ER -