Resistance to amprenavir before and after treatment with lopinavir/ritonavir in highly protease inhibitor-experienced HIV patients

Hamid Hasson, Nicola Gianotti, Anna Danise, Elena Seminari, Enzo Boeri, Silvia Nozza, Antonella Castagna, Adriano Lazzarin

Research output: Contribution to journalArticlepeer-review

Abstract

Genotypes in nine highly protease inhibitor (PI)-experienced patients were studied before and after lopinavir/ritonavir (LPV/r) treatment. Resistance to amprenavir was the rule both before and after LPV/r treatment. Treatment with LPV/r can select for the 50V mutation. In this setting, significant differences in the inference of the amprenavir phenotype from genotype were observed when using different algorithms.

Original languageEnglish
Pages (from-to)123-127
Number of pages5
JournalAIDS (London, England)
Volume18
Issue number1
DOIs
Publication statusPublished - Jan 2 2004

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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