Resistance to amprenavir before and after treatment with lopinavir/ritonavir in highly protease inhibitor-experienced HIV patients

Hamid Hasson; Nicola Gianotti; Anna Danise; Elena Seminari; Enzo Boeri; Silvia Nozza; Antonella Castagna; Adriano Lazzarin

doi:10.1097/00002030-200401020-00015

Resistance to amprenavir before and after treatment with lopinavir/ritonavir in highly protease inhibitor-experienced HIV patients

Hamid Hasson, Nicola Gianotti, Anna Danise, Elena Seminari, Enzo Boeri, Silvia Nozza, Antonella Castagna, Adriano Lazzarin

Research output: Contribution to journal › Article › peer-review

Abstract

Genotypes in nine highly protease inhibitor (PI)-experienced patients were studied before and after lopinavir/ritonavir (LPV/r) treatment. Resistance to amprenavir was the rule both before and after LPV/r treatment. Treatment with LPV/r can select for the 50V mutation. In this setting, significant differences in the inference of the amprenavir phenotype from genotype were observed when using different algorithms.

Original language	English
Pages (from-to)	123-127
Number of pages	5
Journal	AIDS (London, England)
Volume	18
Issue number	1
DOIs	https://doi.org/10.1097/00002030-200401020-00015
Publication status	Published - Jan 2 2004

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1097/00002030-200401020-00015

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Resistance to amprenavir before and after treatment with lopinavir/ritonavir in highly protease inhibitor-experienced HIV patients. / Hasson, Hamid; Gianotti, Nicola; Danise, Anna; Seminari, Elena; Boeri, Enzo; Nozza, Silvia ; Castagna, Antonella; Lazzarin, Adriano.

In: AIDS (London, England), Vol. 18, No. 1, 02.01.2004, p. 123-127.

Research output: Contribution to journal › Article › peer-review

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AU - Boeri, Enzo

AU - Nozza, Silvia

AU - Castagna, Antonella

AU - Lazzarin, Adriano

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AB - Genotypes in nine highly protease inhibitor (PI)-experienced patients were studied before and after lopinavir/ritonavir (LPV/r) treatment. Resistance to amprenavir was the rule both before and after LPV/r treatment. Treatment with LPV/r can select for the 50V mutation. In this setting, significant differences in the inference of the amprenavir phenotype from genotype were observed when using different algorithms.

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Resistance to amprenavir before and after treatment with lopinavir/ritonavir in highly protease inhibitor-experienced HIV patients

Abstract

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