Resistance to Moloney murine sarcoma virus (M-MuSV) tumor induction is associated with natural antibody production to 'endogenous' Moloney leukemia virus (M-MuLV) in BALB/Mo mice

E. D'Andrea, A. De Rossi, L. Chieco-Bianchi

Research output: Contribution to journalArticle

Abstract

BALB/Mo mice are characterized by early expression of 'endogenized' M-MuLV and are resistant to M-MuSV tumor induction. Furthermore, compared to normal BALB/c mice, sera from BALB/Mo mice exhibit a significant reactivty which is specific for M-MuLV when tested in a 125I-labelled Staphylococcus protein-A binding assay. The possible significance of this reactivity in conferrring tumor resistance is explored.

Original languageEnglish
Pages (from-to)511-520
Number of pages10
JournalTumori
Volume67
Issue number6
Publication statusPublished - 1981

ASJC Scopus subject areas

  • Cancer Research

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