Resolution of microsporidial sinusitis and keratoconjunctivitis by itraconazole treatment

Patrizia Rossi, Carlo Urbani, Gianfranco Donelli, Edoardo Pozio

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

PURPOSE: To report successful treatment of ocular infection caused by the microsporidium Encephalitozoon cuniculi in a person with acquired immunodeficiency syndrome (AIDS) and nasal and paranasal sinus infection. METHOD: Case report. RESULTS: Microsporidial infection in a person with AIDS and with chronic sinusitis and keratoconjunctivitis was diagnosed by Weber modified trichrome stain and transmission electron microscopy. Symptoms completely resolved with itraconazole treatment (200 mg/day for 8 weeks) after albendazole therapy (400 mg/day for 6 weeks) was unsuccessful. CONCLUSION: Itraconazole can be recommended in ocular, nasal, and paranasal sinus infection caused by E. cuniculi parasites when treatment with albendazole fails.

Original languageEnglish
Pages (from-to)210-212
Number of pages3
JournalAmerican Journal of Ophthalmology
Volume127
Issue number2
DOIs
Publication statusPublished - Feb 1999

Fingerprint

Keratoconjunctivitis
Itraconazole
Paranasal Sinuses
Sinusitis
Encephalitozoon cuniculi
Albendazole
Unclassified Microsporidia
Acquired Immunodeficiency Syndrome
Infection
Eye Infections
Transmission Electron Microscopy
Parasites

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Resolution of microsporidial sinusitis and keratoconjunctivitis by itraconazole treatment. / Rossi, Patrizia; Urbani, Carlo; Donelli, Gianfranco; Pozio, Edoardo.

In: American Journal of Ophthalmology, Vol. 127, No. 2, 02.1999, p. 210-212.

Research output: Contribution to journalArticle

Rossi, Patrizia ; Urbani, Carlo ; Donelli, Gianfranco ; Pozio, Edoardo. / Resolution of microsporidial sinusitis and keratoconjunctivitis by itraconazole treatment. In: American Journal of Ophthalmology. 1999 ; Vol. 127, No. 2. pp. 210-212.
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