Resolution of recurrent perianal condylomata acuminata by topical cidofovir in patients with HIV infection

C. Martinelli, A. Farese, A. Del Mistro, S. Giorgini, I. Ruffino

Research output: Contribution to journalArticlepeer-review

Abstract

Anogenital condylomata acuminata are the most frequent clinical manifestation of genital human papillomavirus (HPV) infection. Association between human immunodeficiency virus (HIV) and HPV infections is frequent (range: 26-60% in males). Topical cidofovir (a nucleotide analogue antiviral drug active against a broad range of DNA viruses) is a potential treatment for anogenital warts in immunocompromised patients. We treated three HIV-infected patients with HPV perianal condylomas with topical 1% cidofovir in flexible collodion once a day for 2 weeks. The treatment resulted in complete clearance of the HPV lesions. The patients experienced mild transient erythema without any other side-effects. None of the patients relapsed during the 10-14-month follow-up period.

Original languageEnglish
Pages (from-to)568-569
Number of pages2
JournalJournal of the European Academy of Dermatology and Venereology
Volume15
Issue number6
DOIs
Publication statusPublished - 2001

Keywords

  • Cidofovir
  • Condylomas
  • HIV

ASJC Scopus subject areas

  • Dermatology
  • Infectious Diseases

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