Resolution of recurrent perianal condylomata acuminata by topical cidofovir in patients with HIV infection

C. Martinelli, A. Farese, A. Del Mistro, S. Giorgini, I. Ruffino

Research output: Contribution to journalArticle

Abstract

Anogenital condylomata acuminata are the most frequent clinical manifestation of genital human papillomavirus (HPV) infection. Association between human immunodeficiency virus (HIV) and HPV infections is frequent (range: 26-60% in males). Topical cidofovir (a nucleotide analogue antiviral drug active against a broad range of DNA viruses) is a potential treatment for anogenital warts in immunocompromised patients. We treated three HIV-infected patients with HPV perianal condylomas with topical 1% cidofovir in flexible collodion once a day for 2 weeks. The treatment resulted in complete clearance of the HPV lesions. The patients experienced mild transient erythema without any other side-effects. None of the patients relapsed during the 10-14-month follow-up period.

Original languageEnglish
Pages (from-to)568-569
Number of pages2
JournalJournal of the European Academy of Dermatology and Venereology
Volume15
Issue number6
DOIs
Publication statusPublished - 2001

Keywords

  • Cidofovir
  • Condylomas
  • HIV

ASJC Scopus subject areas

  • Dermatology
  • Infectious Diseases

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