Respiratory patterns during sleep in mitochondrial myopathies with ophthalmoplegia

R. Manni, G. Piccolo, P. Banfi, I. Cerveri, C. Bruschi, C. Zoia, A. Tartara

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Nocturnal polygraphic recordings (electroencephalography, electro-oculography, submental and intercostal muscle electromyography, electrocardiography, respiration by thoracic strain gauges and oronasal thermistors) with continuous monitoring of arterial oxyhemoglobin saturation by pulse oximeter were performed in 8 patients with ophthalmoplegia plus. All patients except 1 had normal blood gas values and normal lung volumes associated with a diminished ventilatory response to inhaled CO2 during wakefulness. Four patients showed pathological sleep-related breathing patterns consisting of sleep apneic polygraphic tracings mainly of the central type or of REM-related hypoventilation episodes. It is suggested that these disorders in patients with ophthalmoplegia plus may have a central origin and be related to the underlying metabolic disturbance.

Original languageEnglish
Pages (from-to)12-17
Number of pages6
JournalEuropean Neurology
Volume31
Issue number1
Publication statusPublished - 1991

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Mitochondrial Myopathies
Ophthalmoplegia
Sleep
Respiration
Intercostal Muscles
Hypoventilation
Oxyhemoglobins
Wakefulness
Electromyography
Pulse
Electroencephalography
Electrocardiography
Reference Values
Thorax
Gases
Lung

Keywords

  • Kearns-Sayre syndrome
  • mitochondrial myopathies
  • sleep-related breathing disorders

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Respiratory patterns during sleep in mitochondrial myopathies with ophthalmoplegia. / Manni, R.; Piccolo, G.; Banfi, P.; Cerveri, I.; Bruschi, C.; Zoia, C.; Tartara, A.

In: European Neurology, Vol. 31, No. 1, 1991, p. 12-17.

Research output: Contribution to journalArticle

Manni, R. ; Piccolo, G. ; Banfi, P. ; Cerveri, I. ; Bruschi, C. ; Zoia, C. ; Tartara, A. / Respiratory patterns during sleep in mitochondrial myopathies with ophthalmoplegia. In: European Neurology. 1991 ; Vol. 31, No. 1. pp. 12-17.
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