Abstract
The glucagon and insulin (measured as C-peptide) secretion responses to insulin-induced hypoglycaemia were studied in 6 Type I diabetic patients after successful segmental-pancreatic and renal transplantation. At the time of the study all the patients were independent of insulin and with normal fasting blood glucose (BG) and glycosylated haemoglobin values. Insulin-induced (0.075 IU/kg i.v. insulin over 60 min) hypoglycaemia (38.8 ± 3.23 mg/dl at 60 min) was followed by a spontaneous return of BG to normal in 4 patients, while the remainder required i.v. glucose. Plasma glucagon levels rose in 5 out of 6 patients from basal values of 122.0 ± 5.7 to a peak of 188.0 ± 15.2 pg/ml (p
Original language | English |
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Pages (from-to) | 21-27 |
Number of pages | 7 |
Journal | Diabetes, Nutrition and Metabolism - Clinical and Experimental |
Volume | 1 |
Issue number | 1 |
Publication status | Published - 1988 |
ASJC Scopus subject areas
- Food Science
- Endocrinology
- Medicine (miscellaneous)
- Endocrinology, Diabetes and Metabolism
- Internal Medicine