Abstract
The glucagon and insulin (measured as C-peptide) secretion responses to insulin-induced hypoglycaemia were studied in 6 Type I diabetic patients after successful segmental-pancreatic and renal transplantation. At the time of the study all the patients were independent of insulin and with normal fasting blood glucose (BG) and glycosylated haemoglobin values. Insulin-induced (0.075 IU/kg i.v. insulin over 60 min) hypoglycaemia (38.8 ± 3.23 mg/dl at 60 min) was followed by a spontaneous return of BG to normal in 4 patients, while the remainder required i.v. glucose. Plasma glucagon levels rose in 5 out of 6 patients from basal values of 122.0 ± 5.7 to a peak of 188.0 ± 15.2 pg/ml (p
| Original language | English |
|---|---|
| Pages (from-to) | 21-27 |
| Number of pages | 7 |
| Journal | Diabetes, Nutrition and Metabolism - Clinical and Experimental |
| Volume | 1 |
| Issue number | 1 |
| Publication status | Published - 1988 |
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ASJC Scopus subject areas
- Food Science
- Endocrinology
- Medicine (miscellaneous)
- Endocrinology, Diabetes and Metabolism
- Internal Medicine
Cite this
Response of glucagon and insulin secretion to insulin- induced hypoglycaemia in Type I diabetic patients after pancreatic transplantation. / Bosi, E.; Piatti, P. M.; Secchi, A.; Monti, L. D.; Traeger, J.; Dubernard, J. M.; Pozza, G.
In: Diabetes, Nutrition and Metabolism - Clinical and Experimental, Vol. 1, No. 1, 1988, p. 21-27.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Response of glucagon and insulin secretion to insulin- induced hypoglycaemia in Type I diabetic patients after pancreatic transplantation
AU - Bosi, E.
AU - Piatti, P. M.
AU - Secchi, A.
AU - Monti, L. D.
AU - Traeger, J.
AU - Dubernard, J. M.
AU - Pozza, G.
PY - 1988
Y1 - 1988
N2 - The glucagon and insulin (measured as C-peptide) secretion responses to insulin-induced hypoglycaemia were studied in 6 Type I diabetic patients after successful segmental-pancreatic and renal transplantation. At the time of the study all the patients were independent of insulin and with normal fasting blood glucose (BG) and glycosylated haemoglobin values. Insulin-induced (0.075 IU/kg i.v. insulin over 60 min) hypoglycaemia (38.8 ± 3.23 mg/dl at 60 min) was followed by a spontaneous return of BG to normal in 4 patients, while the remainder required i.v. glucose. Plasma glucagon levels rose in 5 out of 6 patients from basal values of 122.0 ± 5.7 to a peak of 188.0 ± 15.2 pg/ml (p
AB - The glucagon and insulin (measured as C-peptide) secretion responses to insulin-induced hypoglycaemia were studied in 6 Type I diabetic patients after successful segmental-pancreatic and renal transplantation. At the time of the study all the patients were independent of insulin and with normal fasting blood glucose (BG) and glycosylated haemoglobin values. Insulin-induced (0.075 IU/kg i.v. insulin over 60 min) hypoglycaemia (38.8 ± 3.23 mg/dl at 60 min) was followed by a spontaneous return of BG to normal in 4 patients, while the remainder required i.v. glucose. Plasma glucagon levels rose in 5 out of 6 patients from basal values of 122.0 ± 5.7 to a peak of 188.0 ± 15.2 pg/ml (p
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UR - http://www.scopus.com/inward/citedby.url?scp=0024235109&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0024235109
VL - 1
SP - 21
EP - 27
JO - Diabetes, Nutrition and Metabolism - Clinical and Experimental
JF - Diabetes, Nutrition and Metabolism - Clinical and Experimental
SN - 0394-3402
IS - 1
ER -