Response of osteoblast-like MG63 on neoglycosylated collagen matrices

Laura Russo, Antonella Sgambato, Paolo Giannoni, Rodolfo Quarto, Simone Vesentini, Alfonso Gautieri, Laura Cipolla

Research output: Contribution to journalArticlepeer-review

Abstract

Biomaterial surface properties, via introduction of specific signal biomolecules can influence cell adhesion and differentiation processes. Inspired by the monosaccharide motifs found in collagen glycosylation patterns, galactose being one of the most commonly found saccharidic residues, collagen matrices were modified in order to expose galactose residues to cells. The interaction of chemically neoglycosylated matrices was evaluated with osteosarcoma-derived cell line MG63. This journal is

Original languageEnglish
Pages (from-to)1208-1212
Number of pages5
JournalMedChemComm
Volume5
Issue number8
DOIs
Publication statusPublished - 2014

ASJC Scopus subject areas

  • Biochemistry
  • Pharmaceutical Science

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