Abstract
We report two cases of abdominal desmoplastic small round cell tumor (DSRCT) that showed a clinical response to the vinorelbine/low-dose cyclophosphamide combination that has been claimed to be effective for rhabdomyosarcoma. This observation may prompt further investigation into the activity of such a regimen in DSRCT patients with recurrent or refractory disease, with a view to a possible future role as maintenance therapy in controlling minimal residual disease in patients who achieve complete remission with intensive induction multimodality therapy.
Original language | English |
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Pages (from-to) | 864-866 |
Number of pages | 3 |
Journal | Pediatric Blood and Cancer |
Volume | 49 |
Issue number | 6 |
DOIs | |
Publication status | Published - Nov 2007 |
Keywords
- Desmoplastic small round cell tumor
- Low-dose cyclophosphamide
- Metronomic therapy
- Vinorelbine
ASJC Scopus subject areas
- Cancer Research
- Pediatrics, Perinatology, and Child Health
- Hematology